Research Fields

Pharmacology of Natural Compounds

Staff
Topics of research
  • Pharmacological and biochemical analysis of Kampo medicines effective for lifestyle-related and aging-associated diseases
  • Developmemt of natural compound-derived therapeuitc agents for lifestyle-related and chronic inflammatory/allergic diseases
  • Application of naturally occurring various nuclear receptor agonists to prevention/treatment of lifestyle-related diseases

Organic and Medicinal Chemistry

Staff
Topics of research
  • Synthesis, molecular structure and reactivity of novel hypervalent compounds having group 15 and 16 elements
  • Synthesis and property of novel heterocyclic compounds containing main group elements
  • Bio-organometallics: Synthesis and bioactivity of organometallic compounds

Pharmaceutical Health Sciences

Staff
Topics of research
  • Molecular mechanism of harmful metal toxicity (mainly, cadmium)
  • Clarification of new physiological function of metallothionein
  • Disease prevention through functional regulation of biological protection system using organometals

Analytical Chemistry and Biophysics

Staff
Topics of research
  • Molecular mechanism of immune responses
  • Molecular mechanism of allergic reaction
  • Crosstalk between immune and nervous systems
  • Gene transfection mediated by cationic liposomes

Cellular Pharmacology

Staff
Topics of research
  • Transcriptional control of TRP channel expression
  • Epigenetical regulation of TRP channel gene
  • Modification of TRP channel function by clinical drugs

Microbiology

Staff
Topics of research
  • Rapid detection and diagnosis of pathogenic bacteria.
  • Mechanisms of antibacterial resistance and development of drugs effective on multidrug resistant bacteria.
  • Bacterial pathogens and characteristics of emerging and re-emerging infectious disease.
  • Identification of pathogens related to inflammatory bowel disease and clinical development of their treatment and prevention.

Bioorganic Chemistry

Staff
Topics of research
  • Drug discovery based on photophysical chemistry
  • Development of photofunctional organic compounds

Pharmaceutical Health Care and Sciences

Staff
Topics of research
  • Contribution for ensuring effectiveness and safety of medicines in collaboration with hospital and community pharmacies
  • Comparative Study on quality and stability of pharmaceutical products and health foods
  • Investigation on medical evidence of health foods

Pharmaceutics

Staff
Topics of research
  • Membrane transporters in pharmacokinetics and pharmacodynamics
  • Structure, function, and regulation of membrane transporters
  • Personalized medicine

Pharmaceutical Engineering

Staff
Topics of research
  • Nucleic acid drug delivery with PLGA nanopartcile
  • Development of polymeric micelle and nanoparticle for treatment of biofilm infections
  • Solubility improvement technique for poorly water soluble derugs
  • Evaluation and improvement of physical properties of Moh's paste for cancer therapy

Clinical Pharmacy and Sciences

Staff
Topics of research
  • Investigation of pharmaceutical care in community pharmacy
  • Enlightenment of knowledge of osteoporosis care for local residents
  • Establish a prescription check system for the renal failure patients in community pharmacy

Neuropharmacology

Staff
  • Yoshiaki Ohi, Ph.D.
Topics of research
  • Electrophysiological and neuropharmacological analyses of neuron networks and thier synaptic transmission
  • Pathophysiological analyses of central nervous disorders and studies on mode of action of central acting agents

Pediatrics

Staff
Topics of research
  • Cancer drug therapy: Research on L-asparaginase sensitive tumor and its further application to adult cancer patients
  • Pathogenesis and treatment of Kawasaki disease by proteomics analytical research - Establishment of biomarkers of Kawasaki disease severity and search for vasoactive substances to prevent coronary artery lesion
  • Establishment of pediatric pharmacology in Japan - Exploring the Comprehensive role of pharmacists in pediatric medical care - Establishment of therapeutic system in pediatric rheumatology care

Pharmacy Practice and Sciences

Staff
Topics of research
  • Investigation of proper administration of medicines
  • Investigation of quality and stability assessment of medicines
  • Interaction between drugs and medical devices

Medicine

Staff
Topics of research
  • Pathogenesis of diabetic neuropathy and development of new treatments for diabetic neuropathy based on pathogenic mechanisms
  • Evaluation and development of self-monitoring of blood glucose (SMBG) devices and diabetes education
  • Evaluation and development of insulin injection devices and diabetes education
  • Genetic diagnosis of hereditary liver diseases (Hemochromatosis, Wilson disease)