Aichi Gakuin University, School of Pharmacy

Research Fields

Organic and Medicinal Chemistry

Staff
Topics of research
  • Synthesis, molecular structure and reactivity of novel hypervalent compounds having group 15 and 16 elements
  • Synthesis and property of novel heterocyclic compounds containing main group elements
  • Bio-organometallics: Synthesis and bioactivity of organometallic compounds

Bioorganic Chemistry

Staff
Topics of research
  • Relationship between bio-functional molecules and cell proliferetion
  • Aplication of photodynamic therapy for cancer therapy
  • Effective usage of natural products and synthetic compounds based on the genomic informations

Medicinal Resources

Staff
Topics of research
  • Pharmacological and biochemical analysis of Kampo medicines effective for lifestyle-related and aging-associated diseases
  • Developmemt of natural compound-derived therapeuitc agents for lifestyle-related and chronic inflammatory/allergic diseases
  • Application of naturally occurring various nuclear receptor agonists to prevention/treatment of lifestyle-related diseases

Analytical Chemistry and Biophysics

Staff
Topics of research
  • Molecular mechanism of immune responses
  • Molecular mechanism of allergic reaction
  • Crosstalk between immune and nervous systems
  • Gene transfection mediated by cationic liposomes

Pharmaceutical Engineering

Staff
Topics of research
  • Nucleic acid drug delivery with PLGA nanopartcile
  • Development of polymeric micelle and nanoparticle for treatment of biofilm infections
  • Solubility improvement technique for poorly water soluble derugs
  • Evaluation and improvement of physical properties of Moh's paste for cancer therapy

Medicinal Biochemistry

Staff
Topics of research
  • Molecular mechanisms of peritoneal dissemination of scirrhous gastric cancers
  • Metabolome analysis for discovering novel molecular targets to inhibit cancer metastasis
  • Development of fused research field of regenerative medicine and cancer stem cells
  • A new approach of cancer therapy via adipose tissue-derived mesenchymal stem cells

Microbiology

Staff
Topics of research
  • Rapid detection and diagnosis of pathogenic bacteria.
  • Mechanisms of antibacterial resistance and development of drugs effective on multidrug resistant bacteria.
  • Bacterial pathogens and characteristics of emerging and re-emerging infectious disease.
  • Identification of pathogens related to inflammatory bowel disease and clinical development of their treatment and prevention.

Pharmaceutical Health Sciences

Staff
Topics of research
  • Molecular mechanism of harmful metal toxicity (mainly, cadmium)
  • Clarification of new physiological function of metallothionein
  • Disease prevention through functional regulation of biological protection system using organometals

Neuropharmacology

Staff
Topics of research
  • Neuropharmacology of neuronal network in respiratory center, cough center and trigeminal spinal tract
  • Regulatory system of synaptic transmission
  • Analysis of respiratory regulation

Medicine

Staff
Topics of research
  • Studies on the pathogenesis of diabetic complications and the development of their treatments based on pathogenic mechanisms
  • Evaluation and development of self-monitoring of blood glucose (SMBG) devices and diabetes education
  • Evaluation and development of insulin injection device and diabetes education
  • Genetic diagnosis of hereditary liver disease (Hemochromatosis, Wilson disease)

Cellular Pharmacology

Staff
Topics of research
  • Transcriptional control of TRP channel expression
  • Epigenetical regulation of TRP channel gene
  • Modification of TRP channel function by clinical drugs

Pharmaceutics

Staff
Topics of research
  • Membrane transporters in pharmacokinetics and pharmacodynamics
  • Structure, function, and regulation of membrane transporters
  • Personalized medicine

Clinical Pharmacy

Staff
Topics of research
  • Pharmaceutical care clinic for improvement of drug therapy outcomes
  • Promotion of self-medication
  • Development of proper dosage forms for patients and evaluation of medicinal taste

Pharmacy Practice and Sciences

Staff
Topics of research
  • Investigation of proper administration of medicines
  • Investigation of quality and stability assessment of medicines
  • Interaction between drugs and medical devices

Clinical Pharmacodynamics

Staff
Topics of research
  • Development of clinically useful drug delivery system
  • Salivary excretion of drugs and supplements
  • iPS cells for regenerative therapy

Education and Research Division of Pharmacy

Staff
  • Makio Mogi, Ph.D.
  • Yoshifumi Takeda, Ph.D.
Topics of research
  • Bioequivalence studies of generic drugs
  • Clinical monitoring of nutrition management
  • Synthesis of bio-active heterocyclic compounds

Pediatrics

Staff
Topics of research
  • specific amino acid metabolism in pediatric cancer disorders
  • new biomarker in Kawasaki disease or juvenile rheumatic disease
  • specific vasoactive substance in tumor metastatic niche