松村 実生 講師

研究業績一覧
  1. Koyanagi, A., Murata, Y., Matsumura, M., Yasuike, S. Synthesis of sulfenamides from benzoazole-2-thiones with primary and secondary amines using triphenylbismuth dichloride-mediated S-N bond formation reaction. Asian J. Org. Chem., 13, e202400138 (2024).
  2. Matsumura, M., Umeda, A., Sumi, Y., Aiba, N., Murata, Y., Yasuike, S. Bismuth(III)-catalyzed regioselective selenation of Indoles with diaryl diselenides: synthesis of 3-selanylindoles. Molecules, 29, 3227 (2024).
  3. Koyanagi, A., Murata, Y., Takeshita, C., Kato, Y. Matsumura, M., Yasuike, S. Synthesis of tetracyclic benzazole-condensed quinazolinones through triphenylbismuth dichloride assisted cyclodesulfurization. Synthesis, 56, 2109-2117 (2024).
  4. Kawakubo, M., Inoh, Y., Murata, Y., Matsumura, M., Furuno, T., Yasuike, S. Novel mono substituted pyridoimidazoisoquinoliniums via a silver-catalyzed intramolecular cyclization and their applications in cellular imaging. RSC Adv., 14, 9758-9762 (2024).
  5. Kawakubo, M., Inoh, Y., Inaguma, Y., Kokubugata, R., Murata, Y., Matsumura, M., Furuno, T., Yasuike, S. Synthesis and intracellular localization of 5,6-disubsutituted pyrido[1′,2′;2,3]imidazo[5,1-a]isoquinolinium iodides. ChemistrySelect, 8, e202303017 (2023).
  6. Murata, Y., Nishi, Y., Matsumura, M., Yasuike, S. Palladium-Catalyzed Cross-coupling Reaction of Bis(cyclopentadienyl)diaryltitaniums with Terminal Alkynes. Reactions, 4, 657-666 (2023).
  7. Matsumura, M., Nakamura, A., Yanagida, A., Murata, Y., Yasuike, S. Copper-catalyzed three-component reaction of pyrazol-3-ones (antipyrine), triarylbismuthines, and selenium: Synthesis of 4-selanylpyrazol-3-ones. Tetrahedron, 142, 133526 (2023).
  8. Matsumura, M., Nojima, H., Kitamura, Y., Murata, Y., Yasuike, S. Palladium-catalyzed C-H arylation of quinoxalin-2(1H)-ones with triarylantimony difluorides. J. Organometalic. Chem., 989, 122639 (2023).
  9. Koyanagi, A., Murata, Y., Hayakawa, S., Matsumura, M., Yasuike, S., One-pot synthesis of 2-arylated and 2-alkylated benzoxazoles and benzimidazoles based on triphenylbismuth dichloride-promoted desulfurization of thioamides. Beilstein J. Org. Chem., 18, 1479-1487 (2022).
  10. Kawakubo, M., Inaguma, Y., Murata, Y., Matsumura, M., Yasuike, S. Synthesis of novel 5-iodopyrido[1',2';2,3]imidazo[5,1-a]isoquinolinium iodides from 2-(2-ethynylphenyl)imidazo[1,2-a]pyridines via iodocyclization. Tetrahedron Lett., 105, 154054 (2022).
  11. Matsumura, M., Tsukada, K., Sugimoto, K., Murata, Y., Yasuike, S. Synthesis of novel alkynyl imidazopyridinyl selenides: copper-catalyzed tandem selenation of selenium with 2-arylimidazo[1,2-a]pyridines and terminal alkynes. Beilstein J. Org. Chem., 18, 863-871 (2022).
  12. Matsumura, M., Kamiya, T., Kawakubo, M., Hayashi, Y., Hyodo, T., Murata, Y., Yamaguchi, K., Yasuike, S. Synthesis and optical properties of azuleno[1,2-b]benzothiophene and selenophene. Heterocycles, 105, 337-342, (2022).
  13. Murata, Y., Tsuchida, S., Nezaki, R., Kitamura, Y., Matsumura, M., Yasuike, S. Silver-catalyzed three-component reaction of uracils, arylboronic acids, and selenium: synthesis of 5-arylselanyluracils. RSC Adv., 12, 14502, (2022).
  14. Murata, Y., Otake, N., Sano, M., Matsumura, M., Yasuike, S. Copper-catalyzed C−H selenation of 2-substituted benzo[b]furans with diaryl diselenides: Synthesis of 2-substituted 3-selanylbenzo[b]furan derivatives. Asian J. Org. Chem., 10, 2975-2981 (2021).
  15. Murata, Y., Izawa, M., Koyanagi, A., Hayashi, Y., Hyodo, T., Matsumura, M., Yamaguchi, K., Yasuike, S. Construction of dibenzo[d,f][1,3]oxazepine skeleton from 2'-amino-2-hydroxybiphenyl and isothiocyanates via iodine-mediated cyclodesulfurization. Tetrahedron Lett., 73, 153142 (2021).
  16. Matsumura, M., Teramoto, T., Kawakubo, M., Kawahata. M., Murata, Y., Yamaguchi, K., Uchiyama, M., Yasuike, S. Synthesis, structural characterization, and optical properties of benzo[f]naphtho[2,3-b]phosphoindoles. Beilstein J. Org. Chem., 17, 671-677 (2021).
  17. Matsumura, M., Matsuhashi, Y., Kawakubo, M., Hyodo. T., Murata, Y., Kawahata, M., Yamaguchi, K., Yasuike, S. Synthesis, structural characterization, and optical properties of benzene-fused tetracyclic and pentacyclic stiboles. Molecules, 26, 222 (2021).
  18. Kitamura, Y., Murata, Y., Iwai, M., Matsumura, M., Yasuike, S. Palladium-catalyzed C-H arylation of benzofurans with triarylantimony difluorides for the synthesis of 2-arylbenzofurans. Molecules, 26, 97 (2021).
  19. Murata, Y., Kakusawa, N., Arakawa, Y., Hayashi, Y., Morinaga, S., Ueda, M., Hyodo, T., Matsumura, M., Yamaguchi, K., Kurita, J., Yasuike, S. Pd-catalyzed oxidative Heck-type arylation of vinyl ketones, alkenes, and acrylates with Sb-aryltetrahydrodibenz[c,f][1,5]azastibocines. J. Organomet. Chem., 928, 121545 (2020).
  20. Murata, Y., Terazoe, A., Kiba, M., Kitamura, Y., Matsumura, M., Yasuike, S. Liebeskind-Srogl-type cross-coupling reaction of azole-2-thiones with triarylbismuthines: Synthesis of 2-arylazoles. Tetrahedron Lett., 61, 152152 (2020).
  21. Murata, Y., Iwasa, H., Matsumura, M., Yasuike, S. Synthesis of nitriles via the iodine-mediated dehydrosulfurization of thioamides.Chem. Pharm. Bull., 68, 679-681 (2020).
  22. Matsumura, M., Takahashi, T., Yamauchi, H., Sakuma, S., Hayashi, Y., Hyodo, T., Obata, T., Yamaguchi, K., Fujiwara, Y., Yasuike, S. Synthesis and anticancer activity of bis(2-arylimidazo[1,2-a]pyridin-3-yl) selenides and diselenides: the copper-catalyzed tandem C―H selenation of 2-arylimidazo[1,2-a]pyridine with selenium. Beilstein J. Org. Chem., 16, 1075-1083 (2020).
  23. Kitamura, Y., Matsumura, M., Kato, Y., Murata, Y., Yasuike, S. Cascade synthesis of 4-arylcoumarins: Pd-catalyzed arylations and cyclizations with (E)-ethyl 3-(2-hydroxyaryl)acrylates and triarylantimony difluorides. Eur. J. Org. Chem., 2020, 1652-1657 (2020).
    Selected as Very Important Paper (VIP)
  24. Kotani, K., Matsumura, M., Morita, Y., Tomida, J., Kutsuna, R., Nishino, K., Yasuike, S., Kawamura, Y. 13-(2-Methylbenzyl)berberine is a more potent inhibitor of MexXY-dependent aminoglycoside resistance than berberine. Antibiotics, 8, 212-224 (2019).
  25. Murata, Y., Asano, S., Kato, R., Kitamura, Y., Matsumura, M., Yasuike, S. Synthesis of 2-(arylsulfenyl)azoles by copper-catalyzed S-arylation of azole-2-thiones with triarylbismuthines. Catal. Commun., 132, 105808 (2019).
  26. Matsumura, M., Kitamura, Y., Yamauchi, A., Kanazawa, Y., Murata, Y., Hyodo, T., Yamaguchi, K., Yasuike, S. Synthesis of benzo[d]imidazo[2,1-b]benzoselenoazoles: Cs2CO3-mediated cyclization of 1-(2-bromoaryl)benzimidazoles with selenium. Beilstein J. Org. Chem., 15, 2029-2035 (2019).
  27. Matsumura, M., Kawahata, M., Muranaka, A., Hiraiwa, M., Yamaguchi, K., Uchiyama, M., Yasuike, S. Efficient synthesis, structural characterization, and optical properties of 6H-dibenzo[b,h]carbazole and its derivatives. Eur. J. Org. Chem., 2019, 3788-3793 (2019).
  28. Yamada, M., Matsumura, M., Sakaki, E., Yen, S.-y., Kawahata, M., Hyodo, T., Yamaguchi, K., Murata, Y., Yasuike, S. Copper-catalyzed three-component reaction of ethynylstibanes, organic azides, and selenium: A simple and efficient synthesis of novel selenides and diselenides having 1,2,3-triazole rings. Tetrahedron, 75, 1406-1414 (2019).
  29. Murata, Y., Kanasaki, K., Kondo, K., Kakusawa, N., Matsumura, M., Yasuike, S. Visible-light-promoted Se-arylation of diaryl diselenides with 2-phenylimidazopyridines in the presence of ammonium iodide: Synthesis of 2-phenyl-3-(arylselanyl)imidazo[1,2-a]pyridines. Heterocycles, 99, 596-603 (2019).
  30. Kitamura, Y., Murata, Y., Oguri, A., Matsumura, M., Kakusawa, N., Naka, H., Yasuike, S. Pd-catalyzed β-selective C-H arylation of thiophenes with triarylantimony difluorides. Asian J. Org. Chem., 8, 138-143 (2019).
  31. Yamada, M., Matsuura, D., Hasegawa, M., Murata, Y., Kakusawa, N., Matsumura, M., Yasuike, S. Copper-catalyzed cross-coupling reactions of 5-stibano-1,2,3-triazoles with bromoalkynes under aerobic conditions: Synthesis of 5-alkynyl1,2,3-triazoles. J. Organomet. Chem., 871, 79-85 (2018).
  32. Kondo, K., Matsumura, M., Kanasaki, K., Murata, Y., Kakusawa, N., Yasuike, S. Synthesis of 2-aryl-3-(arylselanyl)imidazo[1,2-a]pyridines: copper-catalyzed one-pot two-step Se-Arylation of selenium with imdazopyridines and triarylbismuthanes. Synthesis 50, 2200-2210 (2018).
    Highlighted as a Front Cover
  33. Murata, Y., Matsumoto, N., Miyata, M., Kitamura, Y., Kakusawa, N., Matsumura, M., Yasuike, S. One-pot reaction for the synthesis of N-substituted 2-aminobenzoxazoles using triphenylbismuth dichloride as cyclodesulfurization reagent. J. Organomet. Chem., 859, 18-23 (2018).
  34. Yamada, M., Takahashi, T., Hasegawa, M., Matsumura, M., Ono, K., Fujimoto, R., Kitamura, Y., Murata, Y., Kakusawa, N., Tanaka, M., Obata, T., Fujiwara, Y., Yasuike, S. Synthesis, antitumor activity, and cytotoxicity of 4-substituted 1-benzyl-5-diphenylstibano-1H-1,2,3-triazoles. Bioorg. Med. Chem. Lett., 28, 152-154 (2018).
  35. Yamada, M., Matsumura, M., Takino, F., Murata, Y., Kurata, Y., Kawahata, M., Yamaguchi, K., Kakusawa, N., Yasuike, S. Synthesis of fully functionalized 5-selanyl-1,2,3-triazoles: Copper-catalyzed three-component reaction of ethynylstibanes, organic azides, and diaryl diselenides. Eur. J. Org. Chem., 2018, 170-177 (2018).
  36. Murata, Y., Sugawara, Y., Matsumura, M., Kakusawa, N., Yasuike, S. Microwave-assisted debromination of α-bromoketones with triarylstibanes in water. Chem. Pharm. Bull., 65, 1081-1084 (2017).
  37. Matsumura, M., Yamada, M., Muranaka, A., Kanai, M., Kakusawa, N., Hashizume, D., Uchiyama, M., Yasuike, S. Synthesis and photophysical properties of novel benzophospholo[3,2-b]indole derivatives. Beilstein J. Org. Chem., 13, 2304-2309 (2017).
  38. Kitamura, Y., Matsumura, M., Murata, Y., Yamada, M., Kakusawa, N., Tanaka, M., Okabe, H., Naka, H., Obata, T., Yasuike, S. A versatile synthesis of triarylantimony difluorides by fluorination of triarylstibanes with nitrosyl tetrafluoroborate and their antitumor activity. J. Fluor. Chem., 199, 1-6 (2017).
  39. Yamada, M., Murata, Y., Matsumura, M., Kawahata, M., Saito, K., Kakusawa, N., Yamaguchi, K., Yasuike, S. Synthesis of 5-organostibano-1H-1,2,3-triazoles by Cu-catalyzed azide-alkyne cycloaddition and their application in the acyl-induced deantimonation for the preparation of fully substituted 5-acyl-1,2,3-triazoles. Tetrahedron, 73, 2614-2622 (2017).
  40. Yamada, M., Matsumura, M., Kawahata, M., Murata, Y., Kakusawa, N., Yamaguchi, K., Yasuike, S. Antimony-lithium exchange reaction: Synthesis of 1,4,5-trisubstituted-1,2,3-triazoles by triazolyllithium with electrophiles. J. Organomet. Chem., 834, 83-87 (2017).
  41. Matsumura, M., Takada, R., Ukai, Y., Murata, Y., Kakusawa, N., Yasuike, S. Synthesis of 2-arylquinoxalines: triarylstibane catalyzed oxidative cyclization of α-hydroxy ketones with 1,2-diamines under aerobic conditions. Heterocycles, 93, 75-83 (2016).
    Highlighted in SYNFACTS, 2016, 12 (2), 0128.
  42. Matsumura, M., Sakata, Y., Iwase, A., Kawahata, M., Kitamura, Y., Murata, Y., Kakusawa, N., Yamaguchi, K., Yasuike, S. Copper-catalyzed tandem cyclization of 2-(2-iodophenyl)imidazo[1,2-a]pyridine derivatives with selenium: Synthesis of benzo[b]selenophene-fused imidazo[1,2-a]pyridines. Tetrahedron Lett., 57, 5484-5488 (2016).
  43. Matsumura, M., Muranaka, A., Kurihara, R., Kanai, M., Yoshida, K., Kakusawa, N., Hashizume, D., Uchiyama, M., Yasuike, S. General synthesis, structure, and optical properties of benzothiophene-fused benzoheteroles containing Group 15 and 16 elements. Tetrahedron, 72, 8085-8096 (2016).
  44. Yamada, M., Matsumura, M., Uchida, Y., Kawahata, M., Murata, Y., Kakusawa, N., Yamaguchi, K., Yasuike, S. Copper-catalyzed [3+2] cycloaddition of (phenylethynyl)di-p-tolylstibane with organic azides. Beilstein J. Org. Chem., 12, 1309-1313 (2016).
  45. Matsumura, M., Shibata, K., Ozeki, S., Yamada, M., Murata, Y., Kakusawa, N., Yasuike, S. Synthesis of unsymmetrical diaryl selenides: copper-catalyzed Se-arylation of diaryl diselenides with triarylbismuthanes. Synthesis, 48, 730-736 (2016).
  46. Obata, T., Matsumura, M., Kawahata, M., Hoshino, S., Yamada, M., Murata, Y., Kakusawa, N., Yamaguchi, K., Tanaka, M., Yasuike S. Synthesis, structural characterization and antitumor activity of 2-(di-p-tolylstibano)- and 2-(di-p-tolylbismuthano)-N-p-tolylbenzamide. J. Organomet. Chem., 807, 17-21 (2016).
  47. Matsumura, M., Kumagai, H., Murata, Y., Kakusawa, N., Yasuike, S. Simple and efficient copper-catalyzed synthesis of symmetrical diaryl selenides from triarylbismuthanes and selenium under aerobic conditions. J. Organomet. Chem., 807, 11-16 (2016).
  48. 松村実生：核内受容体の蛍光ラベル化によるアゴニストとアンタゴニストの識別. ファルマシア, トピックス(論文紹介) 51, 987 (2015).
  49. Inoue, K., Urushibara, K., Kanai, M., Yura, K., Fujii, S., Ishigami-Yuasa, M., Hashimoto, Y., Mori, S., Kawachi, E., Matsumura, M., Hirano, T., Kagechika, H., Tanatani, A. Design and synthesis of 4-benzyl-1-(2H)-phthalazinone derivatives as novel androgen receptor antagonists. Eur. J. Med. Chem., 102, 310-319 (2015).
  50. Matsumura, M., Yamada, M., Tsuji, T., Murata, Y., Kakusawa, N., Yasuike, S. Palladium-catalyzed cross-coupling reactions of triarylbismuthanes with terminal alkynes under aerobic conditions. J. Organomet. Chem., 794, 70-75 (2015).
  51. Yasuike, S., Nakata, K., Qin, W., Matsumura, M., Kakusawa, N., Kurita, J. Synthesis of arylboronates by boron-induced ipso-deantimonation of triarylstibanes with boron trihalides and its application in one-pot two-step transmetallation/cross-coupling reactions. J. Organomet. Chem., 788, 9-16 (2015).
  52. Murakami, M., Fujie, T., Matsumura, M., Yoshida, E., Yamamoto, C., Fujiwara, Y., Yasuike, S., Kaji, T. Comparative cytotoxicity of triphenylstibane and fluorine-substituted triarylpnictogens in cultured vascular endothelial cells. Fundam. Toxicol. Sci., 2, 61-66 (2015).
  53. Matsumura, M., Dong Y., Kakusawa, N., Yasuike, S. Pd-Catalyzed P-arylation of triarylantimony dicarboxylates with dialkyl H-phosphites without a base: Synthesis of arylphosphonates. Chem. Pharm. Bull., 63, 130-133 (2015).
  54. Matsumura, M., Muranaka, A., Kakusawa, N., Kurita, J., Hashizume, D. Uchiyama, M., Yasuike, S. Synthesis and structural characterization of a novel organotellurium compound: Dinaphtho[2,3-b;2’,3’-d]tellurophene. Heterocycles, 90, 121-125 (2015).
  55. Mori, S., Takagaki, R., Fujii, S., Matsumura, M., Tanatani, A., Kagechika, H. Lipase-catalyzed asymmetric acylation of boron cluster-containing secondary alcohols. Tetrahedron: Asymmetry, 25, 1505-1512 (2014).
  56. Yasuike, S., Dong, Y., Kakusawa, N., Matsumura, M., Kurita, J. Simple base-free Miyaura-type borylation of triarylantimony diacetates with tetra(alkoxo)diborons under aerobic conditions. J. Organomet. Chem., 765, 80-85 (2014).
  57. Matsumura, M., Tanatani, A., Kaneko, T., Azumaya, I., Masu, H., Hashizume, D., Kagechika, H., Muranaka A., Uchiyama, M. Synthesis of porphyrinylamide and observation of N-methylation induced trans-cis amide conformational alteration. Tetrahedron, 69, 10927-10932 (2013).
  58. Matsumura, M., Tanatani, A., Azumaya, I., Masu, H., Hashizume, D., Kagechika, H., Muranaka A., Uchiyama, M. Unusual conformational preference of an aromatic secondary urea: Solvent-dependent open-closed conformational switching of N,N'-bis(porphyrinyl)urea. Chem. Comm., 49, 2290-2292 (2013).
  59. Okamoto, I., Takahashi, Y., Sawamura, M., Matsumura, M., Masu, H., Katagiri, K., Azumaya, I., Nishino, M., Kohama, Y., Morita, N., Tamura, O., Kagechika, H., Tanatani, A. Redox-Responsive Conformational Alteration of Aromatic Amides Bearing N-Quinonyl System Tetrahedron, 68, 5346-5355 (2012).
  60. Fujimoto, N., Matsumura, M., Azumaya, I., Nishiyama, S., Masu, H., Kagechika, H., Tanatani, A. Molecular Chirality and Chiral Capsule-type Dimer Formation of Cyclic Triamides via Hydrogen-Bonding Interactions. Chem. Commun., 48, 4809-4811 (2012).
  61. Katagiri, K., Furuyama, T., Masu, H., Kato, T., Matsumura, M., Uchiyama, M., Tanatani, A., Tominaga, M., Kagechika, H., Yamaguchi, K., Azumaya, I. Calix[3]amide-based anion receptors: high affinity for fluoride ions and a twisted binding model. Supramol. Chem., 23, 125-130 (2011).
  62. Kakuta, H., Azumaya, I., Masu, H., Matsumura, M., Yamaguchi, K., Kagechika, H., Tanatani, A. Cyclic-tri(N-methyl-meta-benzamide)s: substituent effect on the bowl-shaped conformation in the crystal and solution states. Tetrahedron, 66, 8254-8260 (2010).

スタッフ

愛知学院大学
薬学部　薬化学講座
教授：安池修之
講師：松村実生
講師：村田裕基

アドレス

〒464-8650
愛知県名古屋市千種区楠元町
1-100
Tel. 052-757-6774
Fax. 052-757-6799
交通アクセス

関連リンク

愛知学院大学
愛知学院大学薬学部

English