<おもな招待講演-Invited
Presentations>
K Muraki. CFS/ME International 2025: 4th RID
- Research Innovation and Discovery Conference (Keynote speaker, 12-13, Nov.,
2025, Gold Coast, Australia)
K Muraki. Development
of novel anti-anxiety drugs based on TRP channel studies. HU and AGU
Collaboratory Symposium (Invited
speaker, 7, Feb., 2025, Nagoya, Japan)
K Muraki.
Approach of critical amino acid identification of TRP channels: Integration of
computer science and experimental benchwork. CFS/ME International 2023: RID - Research Innovation and Discovery
Conference (Keynote speaker, 9-10, Nov., 2023, Kings Cliff, Australia)
K Muraki. Comparison of TRPA1 and
PIEZO1 channel functions among species. Ion Channel Modulation Symposium
(ICMS), (Invited speaker, 22nd/23rd June, 2022,
Clare College Cambridge, UK)
K Muraki. うつ病・不安症に対する扁桃体の関与とその神経基盤-TRPC1/4/5サブファミリーの生理機能と精神疾患への関与. 第14回日本不安症学会学術大会 ランチョンセミナー２（招待講演、2022年5月21日、東京）
K Muraki. PIEZO Channels as a
sensor for mechanical stress. CFS/ME International
2021: RID - Research Innovation and Discovery Conference (Keynote speaker,
16-17, Nov., 2021, Gold Coast, Australia)
K Muraki. ストレスセンサーとして働くTRPチャネルとPIEZOチャネル. JT社 製品評価センター講演会 (招待講演、2020年1月, 横浜)
K Muraki. TRP
channels and Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: Overview and
Future Perspectives. CFS/ME International
2018: RID - Research Innovation and Discovery Conference (Keynote speaker,
26-27, Nov., 2018, Gold Coast, Australia)
K Muraki. TRP channels in arthritis, Scandinavian Congress of
Rheumatology (Invited speaker, 5-6, Sept., 2018, Helsinki, Finland)
<おもな発表論文-Main Publications>
2025
村木克彦
& 松原匡希.
TRPA1 チャネルの機能進化. 愛知学院大学薬学会雑誌 第17巻 1-19
(2025)
Natalie Eaton-Fitch, Katsuhiko Muraki, Etianne Martini Sasso, Chandi Magawa, Sonya Marshall-Gradisnik. Analysis of Transient
Receptor Potential Ion Channels in ME/CFS. Methods Mol
Biol. 2025:2920:83-99. doi: 10.1007/978-1-0716-4498-0_6.
Etianne
Martini Sasso, Natalie Eaton-Fitch, Peter Kenneth Smith, Katsuhiko Muraki,
Sonya Marshall-Gradisnik. Low-Dose Naltrexone restored TRPM3 ion channel
function in Natural Killer cells from long COVID patients. Front. Mol.
Biosci 10.3389/fmolb.2025.1582967. (in press).
Mäki-Opas, I., Luostarinen, S., Hämäläinen, M., Muraki, K, Eeva Moilanen. The Contact Allergen Methylisothiazolinone
(MIT) Is a Potent Activator of the TRPA1 Ion Channel. Pharmacol.
Res. & Persp. 13, e70053 (2025). https://doi.org/10.1002/prp2.70053
2024
M
Matsubara,
Y Muraki, H Suzuki, N Hatano & K Muraki. Critical
Amino Acid Residues Regulating TRPA1 Zn2+ Response: A Comparative
Study Across Species. J. Biol. Chem., 300(6):107302
(2024). https://doi.org/10.1016/j.jbc.2024.107302
S
Marshall-Gradisnik, E M Sasso, N Eaton-Fitch, P Smith, J N Baraniuk, K
Muraki. Novel characterization of endogenous transient receptor potential
melastatin 3 ion channels from Gulf War Illness participants. Plos One, 19(6): e0305704. doi:
10.1371/journal.pone.0305704. eCollection 2024.
A.V. Zholos,
I.A. Greenwood, R.J. Lang, C.D. Benham, P.I. Aaronson, C.J. Garland, A.H.
Weston, S.A. Prestwich, D.V. Gordienko, O.V. Povstyan, H. Zhang, L.H. Clapp, V.
Pucovsky, M. Tare, C.J. Fenech, T. Unno, K. Muraki, J. Shi, A.D. Hughes,
T.K. Halstead and D.J. Beech. Thomas (Tom) B. Bolton - a major force in smooth
muscle research. J. Physiol., 2024 Aug;602(15):
3601-3604. doi: 10.1113/JP287062.
E M Sasso, K
Muraki, N Eaton-Fitch, P K Smith, A Jeremijenko, P Griffin, S
Marshall-Gradisnik. Investigation into the restoration of TRPM3 ion channel
activity in post COVID-19 condition: a potential pharmacotherapeutic target. Front. Immunol. 15: 1264702. doi: 10.3389/fimmu.2024.1264702. eCollection 2024.
2022
M
Matsubara,
Y Muraki, N Hatano, H Suzuki & K Muraki. Potent
Activation of Human but Not Mouse TRPA1 by JT010. Int. J. Mol. Sci. 23(22),
1429, (2022).
E M Sasso, K
Muraki, N Eaton-Fitch P Smith, O L Lesslar, G Deed, S Marshall-Gradisnik. Transient receptor potential
melastatin 3 dysfunction in post COVID-19 condition and myalgic
encephalomyelitis/chronic fatigue syndrome patients. Mol. Med.;28(1): 98 (2022).
N
Eaton-Fitch, S D Preez, H Cabanas, K Muraki, D Staines, S
Marshall-Gradisnik. Impaired TRPM3-dependent calcium influx and restoration
using Naltrexone in natural killer cells of myalgic encephalomyelitis/chronic
fatigue syndrome patients. J. Trans. Med.
20, 94 (2022).
2021
N Hatano, M Matsubara, H
Suzuki, Y Muraki & K Muraki. HIF-1α dependent upregulation of
ZIP8, ZIP14, and TRPA1 modify intracellular Zn2+ accumulation in inflammatory
synoviocytes. Int. J. Mol. Sci. 22(12), 6349 (2021). (Based on research from 2011 to 2015)
S
Luostarinen, M Hämäläinen, N Hatano, K Muraki, E Moilanen.
The Inflammatory Regulation of TRPA1 Expression in Human A549 Lung Epithelial
Cells. Pulm. Pharmacol. Ther. 70, 102059 (2021).
H Cabanas, K Muraki, N Eaton-Fitch, D Staines & S
Marshall-Gradisnik. Potential therapeutic benefit of Low
Dose Naltrexone in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Role of
Transient Receptor Potential Melastatin 3 ion channels in pathophysiology and
treatment. Front. Immunol., 12: 687806 (2021).
2020
村木克彦, 今泉祐治. TRPC1／4／5チャネルの生理機能および疾病との関連と標的創薬―特異的な活性化薬・抑制薬の発見による研究展開. Physiological
functions and pathophysiological aspects of TRPC1/4/5 channels and drug
discovery targeting on them. 別冊・医学のあゆみ TRPチャネルのすべて 25-31 (2020).