Research Fields
Pharmacology of Natural Compounds
- Staff
- Topics of research
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- Discovery of naturally occurring compounds with biological activities, such as nuclear receptor ligand activity.
- Isolation, identification, and structural analysis of naturally occurring compounds with novel structures.
- Development of natural compound-derived therapeutic agents for lifestyle-related and chronic inflammatory diseases.
Organic and Medicinal Chemistry
- Staff
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- Shuji Yasuike, Ph.D.
- Mio Matsumura, Ph.D.
- Topics of research
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- Synthesis, molecular structure and reactivity of novel hypervalent compounds having group 15 and 16 elements
- Synthesis and property of novel heterocyclic compounds containing main group elements
- Bio-organometallics: Synthesis and bioactivity of organometallic compounds
Public Health
- Staff
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- Masahiko Satoh, Ph.D.
- Jin-Yong Lee, Ph.D.
- Topics of research
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- Molecular mechanism of harmful metal toxicity (mainly, cadmium)
- Clarification of new physiological function of metallothionein
- Disease prevention through functional regulation of biological protection system using organometals
Analytical Chemistry and Biophysics
- Staff
- Topics of research
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- Molecular mechanism of immune responses
- Molecular mechanism of allergic reaction
- Crosstalk between immune and nervous systems
- Gene transfection mediated by cationic liposomes
Cellular Pharmacology
- Staff
- Topics of research
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- Transcriptional control of TRP channel expression
- Epigenetical regulation of TRP channel gene
- Modification of TRP channel function by clinical drugs
Microbiology
- Staff
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- Yoshiaki Kawamura, Ph.D.
- Junko Tomida, Ph.D.
- Topics of research
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- Rapid detection and diagnosis of pathogenic bacteria.
- Mechanisms of antibacterial resistance and development of drugs effective on multidrug resistant bacteria.
- Bacterial pathogens and characteristics of emerging and re-emerging infectious disease.
- Identification of pathogens related to inflammatory bowel disease and clinical development of their treatment and prevention.
Bioorganic Chemistry
- Staff
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- Shinichiro Kamino, Ph.D.
- Tohru Obata, Ph.D.
- Topics of research
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- Drug discovery based on photophysical chemistry
- Development of photofunctional organic compounds
Pharmaceutical Health Care and Sciences
- Staff
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- Katsuhiko Matsuura, Ph.D.
- Kimihiko Urano, Ph.D.
- Topics of research
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- Contribution for ensuring effectiveness and safety of medicines in collaboration with hospital and community pharmacies
- Comparative Study on quality and stability of pharmaceutical products and health foods
- Investigation on medical evidence of health foods
Pharmaceutics
- Staff
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- Tomohiro Nabekura, Ph.D.
- Yuichi Uwai, Ph.D.
- Topics of research
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- Membrane transporters in pharmacokinetics and pharmacodynamics
- Structure, function, and regulation of membrane transporters
- Personalized medicine
Pharmaceutical Engineering
- Staff
- Topics of research
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- Nucleic acid drug delivery with PLGA nanopartcile
- Development of polymeric micelle and nanoparticle for treatment of biofilm infections
- Solubility improvement technique for poorly water soluble derugs
- Evaluation and improvement of physical properties of Moh's paste for cancer therapy
Clinical Pharmacy and Sciences
- Staff
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- Masami Kawahara, Ph.D.
- Norio Watanabe, Ph.D.
- Topics of research
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- Investigation of pharmaceutical care in community pharmacy
- Enlightenment of knowledge of osteoporosis care for local residents
- Establish a prescription check system for the renal failure patients in community pharmacy
Neuropharmacology
- Staff
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- Yoshiaki Ohi, Ph.D.
- Topics of research
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- Electrophysiological and neuropharmacological analyses of neuron networks and thier synaptic transmission
- Pathophysiological analyses of central nervous disorders and studies on mode of action of central acting agents
Medicine
- Staff
- Topics of research
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- Pathogenesis of diabetic neuropathy and development of new treatments for diabetic neuropathy based on pathogenic mechanisms
- Evaluation and development of self-monitoring of blood glucose (SMBG) devices and diabetes education
- Evaluation and development of insulin injection devices and diabetes education
- Genetic diagnosis of hereditary liver diseases (Hemochromatosis, Wilson disease)
Biochemistry
- Staff
- Topics of research
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- Glycans and RNAs in the malignant progression of cancer cells
- The role of glycans and glycan-binding proteins in osteoclast differentiation and bone metabolism
- Glycans and glycan-binding proteins in intraspecies interactions and infection