研究活動TOP

業績集(衛生薬学講座 2006〜2017)   

2018
原著論文

  1. Lee J.Y., Tokumoto M., Hwang G.W., Satoh M. Comprehensive analysis of BIRC family gene expression changes by mercury compounds and arsenic exposure in neuroblastoma, kidney, and hepatic cells. BPB Rep., 1, 20–24, 2018. PDF
  2. Kobayashi T., Toyama T., Lee J.Y., Miura N., Kuge S., Naganuma A., Hwang G.W. Methylmercury enhances cytotoxicity through inhibition of its activity by a decrease in PTEN solubility. BPB Rep., 1, 1–5, 2018. PDF
  3. Sato M., Toyama T., Lee J.Y., Miura N., Naganuma A., Hwang G.W. Activation of ornithine decarboxylase protects against methylmercury toxicity by increasing putrescine. Toxicol. Appl. Pharmacol., 356, 120–126, 2018. PDF
  4. Ichinomiya M., Shimada A., Ohta N., Inouchi E., Ogihara K., Naya Y., Nagane M., Morita T., Satoh M. Demonstration of mitochondrial damage and mitophagy in cisplatin-mediated nephrotoxicity. Tohoku J. Exp. Med., 246, 1–8, 2018. PDF
  5. Lee J.Y., Tokumoto M., Hwang G.W., Satoh M. Effect of heat shock protein gene expression on cadmium toxicity in human proximal tubular cells. Fundam. Toxicol. Sci., 5, 93–97, 2018. PDF
  6. Tokumoto M., Lee J.Y., Shimada A., Tohyama C., Satoh M. Glutathione has a more important role than metallothionein-I/II against inorganic mercury-induced acute renal toxicity. J. Toxicol. Sci., 43, 275–280, 2018. PDF
  7. Sarma S. N., Saleem A., Lee J.Y., Tokumoto M., Hwang G.W., Chan H.M., Satoh M. Effects of long-term cadmium exposure on urinary metabolite profiles in mice. J. Toxicol. Sci., 43, 89–100, 2018. PDF
  8. Kurita H., Hasegawa T., Seko Y., Nagase H., Tokumoto M., Lee J.Y., Satoh M. Effect of gestational cadmium exposure on fetal growth, polyubiquitinated protein and monoubiqutin levels in the fetal liver of mice. J. Toxicol. Sci., 43, 19–24, 2018. PDF
  9. Yoshida M., Lee J.Y., Satoh M., Watanabe C. Neurobehavioral effects of postnatal exposure to low-level mercury vapor and/or methylmercury in mice. J. Toxicol. Sci., 43, 11–17, 2018. PDF



国際学会発表

  1. Satoh M., Lee J.Y., Tokumoto M. The involvement of glucose transporter gene expression in cadmium renal toxicity. ISES-ISEE 2018. Ottawa, Canada. August 2018.
  2. Lee J.Y., Tokumoto M., Satoh M. The involvement of gene expression of heat shock proteins in Cd renal toxicity. ISES-ISEE 2018. Ottawa, Canada. August 2018.
  3. Tokumoto M., Lee J.Y., Satoh M. Contribution of glutathione and metallothionein to acute toxicity of cadmium. ISES-ISEE 2018. Ottawa, Canada. August 2018.
  4. Satoh M., Lee J.Y., Tokumoto M. Sensitivity of Metallothionein-III Null Mice on Chronic Cadmium Exposure. The 57th Annual Meeting of the Society of Toxicology. San Antonio, Texas, USA. March 2018.
  5. Lee J.Y., Tokumoto M., Satoh M. Cadmium Renal Toxicity through the Suppression of Transcription Activities. The 57th Annual Meeting of the Society of Toxicology. San Antonio, Texas, USA. March 2018.
  6. Tokumoto M., Lee J.Y., Fujiwara Y., Satoh M. Iron accumulation is inhibited by chronically-exposure of cadmium. The 57th Annual Meeting of the Society of Toxicology. San Antonio, Texas, USA. March 2018.


学会発表
  1. 李 辰竜,近藤正規,徳本真紀,◯佐藤雅彦.MEF2A の転写活性抑制を介したカドミウム毒性発現機構フォーラム2018 衛生薬学・環境トキシコロジー.佐世保.20189月.
  2. ◯李 辰竜,小長谷直史,徳本真紀,佐藤雅彦.カドミウム毒性発現におけるヒートショックタンパク質遺伝子の関与フォーラム2018 衛生薬学・環境トキシコロジー.佐世保.20189月.
  3. ◯徳本真紀,道家 瞳,森 稚景,李 辰竜,佐藤雅彦.カドミウムの急性腎毒性に対するグルタチオンの防御効果フォーラム2018 衛生薬学・環境トキシコロジー.佐世保.20189月.
  4. ◯李 辰竜,徳本真紀,佐藤雅彦.MEF2A転写因子の活性抑制を介したカドミウム毒性発現45回日本毒性学会学術年会.大阪.20187月.
  5. ◯徳本真紀,李 辰竜,佐藤雅彦.カドミウムの急性毒性に対するグルタチオンおよびメタロチオネインの意義45回日本毒性学会学術年会.大阪.20187月.
  6. ◯李 辰竜,白鳥義貴,徳本真紀,佐藤雅彦.腎近位尿細管上皮細胞におけるHMGB-1の細胞外放出に及ぼすカドミウムの影響.日本薬学会第138回年会.金沢.20183月.
  7. ◯徳本真紀,李辰竜,藤原泰之,佐藤雅彦.カドミウムによる鉄輸送関連遺伝子の発現変動を介した肝臓中鉄蓄積量の減少.日本薬学会第138回年会.金沢.20183月.

招待講演
  1. 徳本真紀.カドミウム毒性発現におけるユビキチン関連遺伝子の関与.フォーラム2018 衛生薬学・環境トキシコロジー.佐世保.20189月.(部会賞・金原賞 受賞講演)
  2. 徳本真紀.カドミウムによるアポトーシス誘導の分子機構に関する研究.45回日本毒性学会学術年会.大阪.20187月.(奨励賞 受賞講演)
  3. Lee J.Y. Apoptosis related factors involved in cadmium renal toxicity. 2nd World Congress on Pharmacology & Toxicology. Pome, Italy. August 2018. Link
  4. Lee J.Y., Tokumoto M., Satoh M. Novel research on transcriptional pathway in cadmium renal toxicity. The 8th International Congress of Asian Society of Toxicology (ASIATOX 2018). Pattaya, Thailand. June 2018.


過去の業績
2017 2016 2015 2014 2013 2012  
2011 2010 2009 2008 2007 2006