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藤原泰之(Yasuyuki Fujiwara, Ph.D.)1969年生まれ 出生地:兵庫県
略歴
 1992年3月 北陸大学薬学部薬学科 卒業
 1992年4月 北陸大学薬学部 実験助手
 1994年4月 北陸大学薬学部 助手
 2002年4月 北陸大学薬学部 講師
 2006年4月 北陸大学薬学部 助教授
 2007年4月 愛知学院大学薬学部 准教授
 
学位 
博士(薬学)(東北大学、1999年)

学位論文 
鉛による血管内皮修復の阻害とその機序に関する研究 
Link

学外研究員等
北陸大学学術フロンティア客員研究員(2008年2月〜2010年3月)
東京理科大学客員准教授(2013年3月〜)

資格等
薬剤師免許(1992年)、危険物取扱者免状(甲種)(2000年)

専門分野
環境毒性学

研究テーマ
環境汚染金属の血管毒性に関する研究、生体防御システムを活用した疾病の予防と治療に関する研究

教育担当科目
食品衛生・栄養学、環境衛生学、公衆衛生学、基礎薬学実習IV、生体防御薬学特論Ⅱ

所属学会
日本薬学会、日本毒性学会(評議員)、日本衛生学会、日本結合組織学会(評議員)、日本生化学会、日本動脈硬化学会

社会活動 
Journal of Toxicological Sciences 査読委員(2008年1月〜)
ファルマシア地区通信委員(2009年4月〜)
ファルマシア支部アドバイザー(2010年4月〜2011年3月)
ファルマシアアドバイザー(2011年4月〜2012年3月)
日本薬学会 環境衛生部会 財務委員会委員(2013年4月〜)

表彰等

  • 2012年 7月:平成24年度(2012年度) 日本毒性学会 田邊賞 受賞 Link
  • 2011年 7月:平成23年度(2011年度) 日本トキシコロジー学会 田邊賞 受賞 Link
  • 2009年 7月:第3回(2009年度)日本トキシコロジー学会 奨励賞 受賞 Link
  • 2004年11月:Highlighted Paper Selected by Editor-in-Chief(日本薬学会誌 : Biological & Pharmaceutical Bulletin)pdf
  • 2003年10月:第1回(2003年度)日本薬学会 環境・衛生部会賞 受賞 Link

研究費
  • 2012年度〜2014年度科学研究費補助金(代表)基盤研究(C):機能性有機金属化合物・錯体分子によるメタロチオネインの機能調節とその分子機構解明
  • 2009年度〜2010年度科学研究費補助金(代表)若手研究(B):動脈硬化症におけるメタロチオネインの役割と医療への応用
  • 2006年度〜2008年度科学研究費補助金(代表)若手研究(B):無機ヒ素による血管細胞機能障害の分子メカニズム
  • 2004年度〜2005年度科学研究費補助金(代表)若手研究(B):重金属による血管構成細胞のグリコサミノグリカン糖鎖合成異常の解析
  • 2002年度〜2003年度科学研究費補助金(代表)若手研究(B):血管内皮細胞が産生するグリコサミノグリカン糖鎖の微細構造解析とその代謝調節 
  • 2007年度住友財団環境研究助成金(代表):環境汚染金属の毒性を修飾する生体分子の探索

研究業績
原 著 論 文
  1. Fujiwara Y., Yamamoto C., Inagaki T., Satoh M., Kaji T. Bismuth protects against arsenite-induced inhibition of proteoglycan synthesis in cultured vascular endothelial cells. J. Toxicol. Sci., 37, 837-843, 2012. PMID: 22863863
  2. Takahashi Y., Tsuruta S., Honda A., Fujiwara Y., Satoh M., Yasutake A. Effect of dental amalgam on gene expression profiles in rat cerebrum, cerebellum, liver and kidney. J. Toxicol. Sci., 37, 663-666, 2012. PMID: 22688007
  3. Tokumoto M., Fujiwara Y., Shimada A., Hasegawa T., Seko Y., Nagase H., Satoh M. Cadmium toxicity is caused by accumulation of p53 through the down-regulation of Ube2d family genes in vitro and in vivo. J. Toxicol. Sci., 36, 191-200, 2011. J-STAGE 〜平成24年度 日本毒性学会・田邊賞受賞論文〜
  4. Fujiwara Y., Banno H., Shinkai Y., Yamamoto C., Kaji T., Satoh M. Protective effect of pretreatment with cilostazol on cytotoxicity of cadmium and arsenite in cultured vascular endothelial cells. J. Toxicol. Sci., 36, 155-161, 2011. J-STAGE
  5. Fujiwara Y., Honda A., Yamamoto C., Kaji T., Satoh M. DNA microarray analysis of human coronary artery endothelial cells exposed to cadmium. J. Toxicol. Sci., 36, 141-143, 2011. pdf & PMID: 21297354
  6. Tokumoto M., Ohtsu T., Honda A., Fujiwara Y., Nagase H., Satoh M. DNA microarray analysis of normal rat kidney epithelial cells treated with cadmium. J. Toxicol. Sci., 36, 127-129, 2011. pdf & PMID: 21297351
  7. Ishiguro, M., Mishiro, K., Fujiwara, Y., Chen, H., Izuta, H., Tsuruma, K., Shimazawa, M., Yoshimura, S., Satoh, M., Iwama, T., Hara, H. Phosphodiesterase-III inhibitor prevents hemorrhagic transformation induced by focal cerebral ischemia in mice treated with tPA. PLoS ONE, 5(12), e15178, 2010. Link
  8. Honda, A., Komuro, H., Shimada, A., Hasegawa, T., Seko, Y., Nagase, H., Hozumi, I., Inuzuka, T., Hara, H., Fujiwara, Y., Satoh, M. Attenuation of cadmium-induced testicular injury in metallothionein-III null mice. Life. Sci., 87, 545-550, 2010. PMID: 20851133
  9. Hirooka, T., Fujiwara, Y., Shinkai, Y., Yamamoto, C., Yasutake, A., Satoh, M., Eto, K., Kaji, T. Resistance of human brain microvascular endothelial cells in culture to methylmercury: Cell-density-dependent defense mechanisms. J. Toxicol. Sci., 35, 287-294, 2010. PMID: 20519836
  10. Fujiwara, Y., Honda, A., Satoh, M. DNA microarray gene expression analysis of human vascular endothelial cells exposed to arsenite. J. Toxicol. Sci., 35, 275-278, 2010. PMID: 20371982
  11. Honda, A., Komuro, H., Hasegawa, T., Seko, Y., Shimada, A., Nagase, H., Hozumi, I., Inuzuka, T., Hara, H., Fujiwara, Y., Satoh, M. Resistance of metallothionein-III null mice to cadmium-induced acute hepatotoxicity. J. Toxicol. Sci., 35, 209-215, 2010. PMID: 20371971 〜平成23年度 日本トキシコロジー学会・田邊賞受賞論文〜
  12. Honda, A., Komuro, H., Nagase, H., Hozumi, I., Inuzuka, T., Hara, H., Fujiwara, Y., Satoh, M. Microarray analysis of the liver in metallothionein-III null mice treated with cadmium. J. Toxicol. Sci., 35, 271-273, 2010. PMID: 20371981
  13. Hirooka, T., Fujiwara, Y., Minami, Y., Ishii, A., Ishigooka, M., Shinkai, Y., Yamamoto, C., Satoh, M., Yasutake, A., Eto, K., Kaji, T. Cell-density-dependent methylmercury susceptibility of cultured human brain microvascular pericytes. Toxicol. In Vitro, 24, 835-841, 2010. PMID: 20005941
  14. Fujiwara, Y., Kitagawa, T., Shinkai, Y., Kaji, T., Satoh, M. Cilostazol induces metallothionein expression in vascular cells. Yakugaku Zasshi, 129, 1415-1422, 2009.
  15. Hirooka, T., Fujiwara, Y., Inoue, S., Shinkai, Y., Yamamoto, C., Satoh, M., Yasutake, A., Eto, K., Kaji, T. Suppression of fibroblast growth factor-2 expression: Possible mechanism underlying the methylmercury-induced inhibition of repair of wounded monolayers of cultured human brain microvascular endothelial cells. J. Toxicol. Sci., 34, 433-439, 2009.
  16. Fujiwara, Y., Mikami, C., Nagai, M., Yamamoto, C., Hirooka, T., Satoh, M., Kaji, T. Homocysteine inhibits proteoglycan synthesis in cultured bovine aortic smooth muscle cells. J. Health Sci., 54, 56-65, 2008.
  17. Fujiwara, Y., Yamamoto, C., Hirooka, T., Terada, N., Satoh, M., Kaji, T. Arsenite but not arsenate inhibits general proteoglycan synthesis in cultured arterial smooth muscle cells. J. Toxicol. Sci., 33, 487-492, 2008.
  18. Yamamoto, C., Urano, U., Fujiwara, Y., Kaji T. Adiponectin as an inducer of decorin synthesis in cultured vascular smooth muscle cells. Life Sci., 83, 447-452, 2008.
  19. Hirooka, T., Fujiwara, Y., Yamamoto, C., Yasutake, A., Kaji, T. Methylmercury retards the repair of wounded monolayer of human brain microvascular endothelial cells by inhibiting their proliferation without nonspecific cell damage. J. Health Sci., 53, 450-456, 2007.
  20. Kaji, T., Yamamoto, C., Oh-i, M., Fujiwara, Y., Yamazaki, Y., Morita, T., Plaas, A.H., Wight, T.N. The vascular endothelial growth factor VEGF165 induces perlecan synthesis via VEGF receptor-2 in cultured human brain microvascular endothelial cells. Biochim. Biophys. Acta., 1760, 1465-1474, 2006.
  21. Ida, M., Shuo, T., Hirano, K., Tokita, Y., Nakanishi, K., Matsui, F., Aono, S., Fujita, H., Fujiwara, Y., Kaji, T., Oohira, A. Identification and Functions of Chondroitin Sulfate in the Milieu of Neural Stem Cells. J. Biol. Chem., 281, 5982-5991, 2006.
  22. Fujiwara, Y., Plaas, A.H., Kaji, T. Proteoglycan synthesis is not influenced by zinc in proliferating bovine aortic endothelial cells in culture. J. Health Sci., 51, 720-727, 2005.
  23. Yamamoto, C., Deng, X., Fujiwara, Y., Kaji, T. Proteoglycans predominantly synthesized by human brain microvascular endothelial cells in culture are perlecan and biglyan. J. Health Sci., 51, 576-583, 2005.
  24. Fujiwara, Y., Nakase, Y., Kaji, T., Sodium arsenite inhibits proteoglycan synthesis by vascular endothelial cells in culture. J. Health Sci., 51, 461-468 (2005)
  25. Fujiwara, Y., Mitani, M., Yasuike, S., Kurita, J., Kaji, T., An organobismuth compound that exhibits selective cytotoxicity to vascular endothelial cells in vitro. J. Health Sci., 51, 333-340 (2005)
  26. Yamamoto, C., Wakata, T., Fujiwara, Y., Kaji, T. Induction of synthesis of a large heparan sulfate proteoglycan, perlecan, by thrombin in cultured human coronary smooth muscle cells. Biochim. Biophys. Acta., 1722, 92-102, 2005.
  27. Yamamoto, C., Shimada, S., Fujiwara, Y., Lee, J.B., Hayashi, T., Kaji, T. Proteoglycan released from cultured bovine aortic endothelial cell layers by sodium spirulan are both perlecan and biglycan. Biol. Pharm. Bull., 28, 32-36, 2005.
  28. Yamamoto, C., Sugato, M., Fujiwara, Y., Kaji, T. Selective promotion of plasminogen activator inhibitor-1 secretion by activation of proteinase-activated receptor-1 in cultured human brain microvascular pericytes: comparison with endothelial cells. Biol. Pharm. Bull., 28, 208-211, 2005.
  29. Kaji, T., Sakurai, S., Yamamoto, C., Fujiwara, Y., Yamagishi, S., Yamamoto, H., Kinsella, M.G., Wight, T.N., Characterization of chondroitin/dermatan sulfate proteoglycans synthesized by bovine retinal pericytes in culture. Biol. Pharm. Bull., 27, 1763-1768, 2004.  Highlighted Paper Selected by Editor-in-Chief
  30. Kaji, T., Shimada, S., Yamamoto, C., Fujiwara, Y., Lee, J.B., Hayashi, T., Stimulation of proteoglycan release from cultured vascular endothelial cell layers by sodium spirulan. J. Health Sci., 50, 654-659, 2004.
  31. Fujiwara, Y., Kaji, T., Plaas, A.H., Disaccharide composition of glycosaminoglycan chains in growing vascular endothelial cells in culture after exposure to lead. J. Health Sci., 50, 660-666, 2004.
  32. Kaji, T., Okabe, S., Shimada, S., Yamamoto, C., Fujiwara, Y., Lee, J.B., Hayashi, T., Sodium spirulan as a potent inhibitor of arterial smooth muscle cell proliferation in vitro. Life Sci., 74, 2431-2439, 2004.
  33. Fujiwara, Y., Yamamoto, C., Kaji, T., Plaas, A.H. Analysis of chondroitin/dermatan sulfate microstructure in cultured vascular smooth muscle cells after exposure to lead and cadmium. J. Health Sci., 49, 534-540, 2003.
  34. Kaji, T., Hiraga, S., Yamamoto, C., Fujiwara, Y., Ueda, Y., Zizaki, F., Iwata, K., Katsuda, S., Nakanishi, I., Vascular smooth muscle cells in culture express tumor necrosis factor-α that suppresses collagen synthesis depending on cell density. J. Health Sci., 49, 115-122, 2003.
  35. Fujiwara, Y., Kaji, T. Suppression of proteoglycan synthesis by calcium ionophore A23187 in cultured vascular endothelial cells: Implication of intracellular calcium accumulation in lead inhibition of endothelial proteoglycan synthesis. J. Health Sci., 48, 460-466, 2002.
  36. Kaji, T., Hiraga, S., Yamamoto, C., Fujiwara, Y., Ueda, Y., Zizaki, F., Iwata, K., Okada, Y., Katsuda, S. Effects of tumor necrosis factor-α on the synthesis of DNA, the secretion of matrix metalloproteinases/tissue Inhibitors of metalloproteinases, and the activity of invasive migration in cultured vascular smooth muscle cells. J. Health Sci., 48, 354-358, 2002.
  37. Kaji, T., Fujiwara, Y., Hamada, C., Yamamoto, C., Shimada, S., Lee, J.B., Hayashi, T. Inhibition of cultured bovine aortic endothelial cell proliferation by sodium spirulan, a new sulfated polysaccharide isolated from Spirulina platensis. Planta Med., 68, 505-509, 2002.
  38. Kaji, T., Shimada, S., Yamamoto, C., Fujiwara, Y., Lee, J.B., Hayashi, T. Inhibition of the association of proteoglycans with cultured vascular endothelial cell layers by calcium and sodium spirulan. J. Health Sci., 48, 250-255, 2002.
  39. Kaji, T., Fujiwara, Y., Inomata, Y., Hamada, C., Yamamoto, C., Shimada, S., Lee, J.B., Hayashi, T. Repair of wounded monolayers of cultured bovine aortic endothelial cells is inhibited by calcium spirulan, a novel sulfated polysaccharide isolated from Spirulina platensis. Life Sci., 70, 1841-1848, 2002.
  40. Fujiwara, Y., Tsumura, N., Yamamoto, C., Kaji, T., Differential effects of cadmium on proteoglycan synthesis of arterial smooth muscle cells: increase in small dermatan sulfate proteoglycans, biglycan and decorin, in the extracellular matrix at low cell density. Toxicology, 170, 89-101, 2002.
  41. Fujiwara, Y., Yamamoto, C., Kaji, T. Proteoglycan synthesis by cultured bovine aortic smooth muscle cells after exposure to lead: lead selectively inhibits the synthesis of versican, a large chondroitin sulfate proteoglycan. Toxicology, 154, 9-19, 2000.
  42. Kaji, T., Miyajima, S., Yamamoto, C., Fujiwara, Y., Sakurai, S., Yamagishi, S., Sueishi, K., Yamamoto, H. Selective increase in decorin core mRNA level in cultured vascular smooth muscle cells after exposure to advanced glycation endproducts. J. Health Sci., 46, 223-227, 2000.
  43. Kaji, T., Yamada, A., Miyajima, S., Yamamoto, C., Fujiwara, Y., Wight, T.N., Kinsella, M.G. Cell density-dependent regulation of proteoglycan synthesis by transforming growth factor-β1 in cultured bovine aortic endothelial cells. J. Biol. Chem., 275, 1463-1470, 2000.
  44. Fujiwara, Y., Kaji, T. Lead inhibits the core protein synthesis of a large heparan sulfate proteoglycan perlecan by proliferating vascular endothelial cells in culture. Toxicology, 133, 159-169, 1999.
  45. Fujiwara, Y., Kaji, T. Possible mechanism for lead inhibition of vascular endothelial proliferation: a lower response to basic fibroblast growth factor through inhibition of heparan sulfate synthesis. Toxicology, 133, 147-157, 1999.
  46. Fujiwara, Y., Watanabe, S., Sakamoto, M., Kaji, T. Repair of wounded monolayers of cultured vascular endothelial cells after simultaneous exposure to lead and zinc. Toxicol. Lett., 94, 181-188, 1998.
  47. Fujiwara, Y., Watanabe, S., Kaji, T. Promotion of cultured vascular smooth muscle cell proliferation by low levels of cadmium. Toxicol. Lett., 94, 175-180, 1998.
  48. Ohkawara, S., Yamamoto, C., Fujiwara, Y., Sakamoto, M., Kaji, T. Cadmium induces the production of high molecular weight heparan sulfate proteoglycan molecules in cultured vascular endothelial cells. Environ. Toxicol. Pharmacol., 3, 187-194, 1997.
  49. Fujiwara, Y., Kaji, T. Zinc potentiates the stimulation by basic and acidic fibroblast growth factor on the proliferation of cultured vascular smooth muscle cells. Res. Commun. Mol. Pathol. Pharmacol., 97, 95-106, 1997.
  50. Mishima, A., Yamamoto, C., Fujiwara, Y., Kaji, T. Tolerance to cadmium cytotoxicity is induced by zinc through non-metallothionein mechanism as well as metallothionein induction in cultured cells. Toxicology, 118, 85-92, 1997.
  51. Fujiwara, Y., Kaji, T., Sakurai, S., Sakamoto, M., Kozuka, H. Inhibitory effect of lead on the repair of wounded monolayers of cultured vascular endothelial cells. Toxicology, 117, 193-198, 1997.
  52. Kaji, T., Miyamoto, A., Yamamoto, C., Fujiwara, Y., Miyajima, S., Koizumi, F. Basic fibroblast growth factor-induced glycosaminoglycan production in cultured vascular endothelial cells results from enhanced protein synthesis mediated by the lipoxygenase pathway. Life Sci., 60, 873-881, 1997.
  53. Kaji, T., Ohkawara, S., Nakajima, M., Yamamoto, C., Fujiwara, Y., Miyajima, S., Koizumi, F. Lead-induced alteration of heparan sulfate proteoglycans in cultured vascular endothelial cells. Toxicology, 118, 1-10, 1997.
  54. Yokozawa, T., Tuji, A., Hattori, M., Oura, H., Kaji, T., Fujiwara, Y., Wakaki, K., Koizumi, F., Shimizu, M. Effect of Chinese medical preparation, hokoei-to, on lipids in blood and involvement of cells of vascular origin. Phytother. Res., 10, 224-227, 1996.
  55. Mishima, A., Yamamoto, C., Fujiwara, Y., Kaji, T. Metallothionein-independent protection by low levels of zinc against cadmium cytotoxicity in cultured cells. Res. Commun. Pharmacol. Toxicol., 1, 199-210, 1996.
  56. Ohkawara, S., Kaji, T., Yamamoto, C., Fujiwara, Y., Sakamoto, M. Interaction between cadmium and zinc in the production and sulfation of glycosaminoglycans in cultured bovine vascular endothelial cells. J. Toxicol. Environ. Health, 47, 183-193, 1996.
  57. Kaji, T., Inada, M., Yamamoto, C., Fujiwara, Y., Koizumi, F. Cyclic AMP-dependent pathway that mediates suppressive regulation of glycosaminoglycan production in cultured vascular endothelial cells. Tromb. Res., 82, 389-397, 1996.
  58. Fujii, N., Kaji, T., Yamamoto, C., Fujiwara, Y., Koizumi, F. Phorbol 12-myristate 13-acetate stimulates the release of glycosaminoglycans from cultured vascular endothelial cells: possible involvement of protein kinase C activation. Thromb. Res., 82, 379-387, 1996.
  59. Kaji, T., Suzuki, M., Yamamoto, C., Imaki, Y., Miyajima, S., Fujiwara, Y., Sakamoto, M., Kozuka, H. Sensitive response of cultured vascular smooth-muscle cells to cadmium cytotoxicity: comparison with cultured vascular endothelial cells and kidney epithelial LLC-PK1 cells. Toxicol. Lett., 89, 131-137, 1996.
  60. Kaji, T., Mishima, A., Yamamoto, C., Fujiwara, Y., Sakamoto, M., Kozuka, H., Koizumi, F. Bismuth induces metallothionein but does not protect against cadmium cytotoxicity in cultured vascular endothelial cells. Bull. Environ. Contam. Toxicol., 56, 630-634, 1996.
  61. Kaji, T., Yamamoto, C., Miyajima, S., Suzuki, M., Fujiwara, Y., Sakamoto, M., Koizumi, F. Vascular smooth muscle cells in culture are highly sensitive to cadmium cytotoxicity without species-related differences: comparison with Chang Liver cells. Biol. Pharm. Bull., 18, 1392-1395, 1995.
  62. Kaji, T., Fujiwara, Y., Sakurai, S., Yamamoto, C., Kozuka, H., Koizumi, F. Zinc promotes the repair of wounded monolayers of cultured vascular endothelial cells. Res. Commun. Mol. Pathol. Pharmacol., 89, 189-198, 1995.
  63. Fujiwara, Y., Kaji, T., Yamamoto, C., Sakamoto, M., Kozuka, H. Stimulatory effect of lead on the proliferation of cultured vascular smooth-muscle cells. Toxicology, 98, 105-110, 1995.
  64. Kaji, T., Mishima, A., Machida, M., Yabusaki, K., Suzuki, M., Yamamoto, C., Fujiwara, Y., Sakamoto, M., Kozuka, H. Comparative cytotoxicity of exogenous cadmium-metallothionein and cadmium ion in cultured vascular endothelial cells. Bull. Environ. Contam. Toxicol., 54, 501-506, 1995.
  65. Kaji, T., Yamamoto, C., Suzuki, M., Miyajima, S., Fujiwara, Y., Sakamoto, M., Koizumi, F. Induction of metallothionein by thrombin in cultured vascular endothelial and smooth muscle cells. Biol. Pharm. Bull., 18, 1272-1274, 1995.
  66. Kaji, T., Fujiwara, Y., Yamamoto, C., Sakamoto, M., Kozuka, H. Stimulation of cultured vascular smooth muscle cell proliferation by thrombospondin is potentiated by zinc. Biol. Pharm. Bull., 18, 1264-1266, 1995.
  67. Kaji, T., Fujiwara, Y., Hoshino, M., Yamamoto, C., Sakamoto, M., Kozuka, H. Inhibitory effect of lead on the proliferation of cultured vascular endothelial cells. Toxicology, 95, 87-92, 1995.
  68. Kaji, T., Suzuki, M., Yamamoto, C., Imaki, Y., Mishima, A., Fujiwara, Y., Sakamoto, M., Kozuka, H. Induction of metallothionein synthesis by bismuth in cultured vascular endothelial cells. Res. Commun. Mol. Pathol. Pharmacol., 86, 25-35, 1994.
  69. Kaji, T., Fujiwara, Y., Yamamoto, C., Sakamoto, M., Kozuka, H. Stimulation by zinc of cultured vascular endothelial cell proliferation: Possible involvement of endogenous basic fibroblast growth factor. Life Sci., 55, 1781-1787, 1994.
  70. Kaji, T., Fujiwara, Y., Koyanagi, E., Yamamoto, C., Mishima, A., Sakamoto, M. Kozuka, H. Protective effect of copper against cadmium cytotoxicity on cultured vascular endothelial cells. Toxicol. Lett., 63, 13-20, 1992.


総 説
  1. Fujiwara Y., Satoh M. Protective Role of Metallothionein in chemical and radiation carcinogenesis. Curr. Pharm. Biotechnol., 14, 394-399, 2013. PMID: 23590136
  2. Fujiwara Y., Lee J.Y., Tokumoto M., Satoh M. Cadmium renal toxicity via apoptotic pathways. Biol. Pharm. Bull., 35, 1892-1897, 2012. PDF
  3. 佐藤友子, 山本千夏, 藤原泰之, 鍜冶利幸. 血管内皮細胞のプロテオグリカン代謝の制御を介した外来性糖鎖の活性. Yakugaku Zasshi, 128, 717-723, 2008.
  4. 浦野晶子, 山本千夏, 藤原泰之, 鍜冶利幸. 動脈硬化進展の鍵分子プロテオグリカン: その特性および合成調節. Yakugaku Zasshi, 128, 365-375, 2008.
  5. Yamamoto, C., Fujiwara, Y. and Kaji, T. The biological effects of depolymerized sodium spirulan and sulfated colominic acid on vascular cells are beneficial in preventing atherosclerosis. J. Health Sci., 52, 205-210, 2006.
  6. Fujiwara, Y. Cell biological study on abnormal proteoglycan synthesis in vascular cells exposed to heavy metals. J. Health Sci., 50, 197-204, 2004.
  7. Fujiwara, Y. and Kaji, T. Inhibition of the repair of injured endothelial cell monolayers by lead and its possible mechanisms. J. Health Sci., 46, 1-4, 2000.


著 書
教科書・辞典
  1. 藤原泰之(分担執筆). コンパス衛生薬学ー健康と環境ー 初版 (鍜冶利幸・佐藤雅彦編集), 南江堂, 2011.
  2. 藤原泰之(分担執筆). 衛生薬学サブノート 初版 (岡野登志夫・山﨑裕康・佐藤雅彦・鍜冶利幸編集), 廣川書店, 2009.
  3. 藤原泰之(分担執筆). 新衛生薬学実習 初版 (手塚雅勝・山本郁男編集), 地人書館, 2006.
その他
  1. 藤原泰之、木村朋紀 若手が切り開くMolecular Toxicology 5 —化学物質に対する感受性を決定する生体システム—.(誌上シンポジウム:日本薬学会第130年会シンポジウムS33序文)Yakugaku Zasshi, 131, 353-354, 2011.
  2. 藤原泰之. 緑膿菌の巧妙な戦略. ファルマシア, 36, 162-163, 2002.
そ の 他
  1. 藤原泰之.メラミンによる食品汚染について.日本薬学会 環境・衛生部会ホームページ「環境・衛生薬学トピックス」2010.2.1〜掲載開始 Link
  2. 藤原泰之.奨励賞を受賞して.J. Toxicol. Sci., 34 (5), app. 66, 2009.
  3. 藤原泰之.薬学を目指す諸君へ”生体と金属”.平成20年度愛知学院大学薬学部オープンキャンパス模擬講義.平成20年10月5日
  4. 藤原泰之.『食』と健康〜22世紀に向けて〜 食品汚染問題を考える.平成21年度春季愛知学院大学公開講座.平成21年5月30日
  5. 藤原泰之.『食』と健康〜22世紀に向けて〜 食品汚染問題を考える.平成21年度名古屋市連携公開講座.平成21年6月5日
  6. 藤原泰之.食品汚染問題を考える (1), (2).平成21年度愛知学院大学放送公開講座.平成21年10月11日、18日
  7. 藤原泰之.食の安全とヒトの健康 〜薬剤師の果たす役割〜.平成22年度愛知学院大学薬学部オープンキャンパス模擬講義.平成22年7月31日、8月1日