2024年

Kawakubo, M., Inoh, Y., Murata, Y. Matsumura, M., Furuno, T., Yasuike S.: Novel mono substituted pyridoimidazoisoquinoliniums via a silvercatalyzed intramolecular cyclization and their applications in cellular imaging. RSC Adv., 14, 9758. (2024)


2023年

Kawakubo, M., Inoh, Y., Inaguma, Y., Kokubugata, R., Murata, Y., Matsumura, M., Furuno, T., Yasuike, S.: Synthesis and intracellular localization of 5,6-disubsutituted pyrido[1’,2’;2,3]imidazo[5,1-a]isoquinolinium Iodides. ChemistrySelect, 8, e202303017. (2023)


2022年

Sugimoto, H., Fukuda, S., Yokawa, S., Hori, M., Ninomiya, H., Sato, T., Miyazawa, K., Kawai, T., Furuno, T., Inouye, S., Goto, S., Suzuki, T.: Visualization of osteocalcin and bone morphogenetic protein 2 (BMP2) secretion from osteoblastic cells by bioluminescence imaging. Biochem. Biophys. Res. Commun., 635, 203-209. (2022)

Nakao, Y., Yokawa, S., Kohno, T., Suzuki, T., Hattori, M.: Visualization of reelin secretion from primary cultured neurons by bioluminescence imaging. J. Biochem., 171, 591-598. (2022)


2021年

Suzuki, R., Inoh ,Y., Yokawa, S., Furuno, T., Hirashima, N.: Receptor dynamics regulates actin polymerization state through phosphorylation of cofilin in mast cells. Biochem. Biophys. Res. Commun., 534, 714-719. (2021)

Goto, S., Ozaki, Y., Ozawa, F., Mizutani, E., Kitaori, T., Suzumori, N., Blomgren, K., Furuno, T., Sugiura-Ogasawara, M.: The investigation of calpain in human placenta with fetal growth restriction. Am. J. Reprod. Immunol., 85, e13325. (2021)


2020年

Inoh, Y., Tsuchiya, Y., Nakanishi, Y., Yokawa, S., Furuno, T.: Involvement of intracellular caveolin-1 distribution in the suppression of antigen-induced mast cell activation by cationic liposomes. Cell Biol. Int., 44, 1068-1075. (2020)

Inoh, Y., Hirose, T., Yokoi, A., Yokawa, S., Furuno, T.: Effects of lipid composition in cationic liposomes on suppression of mast cell activation. Chem. Phys. Lipids, 231, 104948. (2020)


2019年

Suzuki, R., Inoh, Y., Yokawa, S., Suzuki, R., Furuno, T., Hirashima, N.: Monomer hapten and hapten-specific IgG inhibit mast cell activation evoked by multivalent hapten with different mechanisms. Eur. J. Immunol., 49, 2172-2183. (2019)

Shiki, A., Inoh, Y., Yokawa, S., Furuno, T.: Inhibition of degranulation in mast cells attached to a hydrogel through defective microtubule tracts. Exp. Cell Res., 381, 248-255. (2019)

Shiki, A., Inoh, Y., Yokawa, S., Furuno, T.: Promotion of microtubule acetylation plays an important role in degranulation of antigen-activated mast cells. Inflamm. Res., 68, 181-184. (2019)

Kanki, H., Sasaki, T., Matsumura, S., Yokawa, S., Yukami, T., Shimamura, M., Sakaguchi, M., Furuno, T., Suzuki, T., Mochizuki, H.: β-arrestin-2 in PAR-1-biased signaling has a crucial role in endothelial function via PDGF-β in stroke. Cell Death Dis., 10, 100. (2019)


2018年

Watabe, K., Yokawa, S., Inoh, Y., Suzuki, T., Furuno, T.: Decreased intracellular granule movement and glucagon secretion in pancreatic α cells attached to superior cervical ganglion neurites. Mol. Cell. Biochem., 446, 83-89. (2018)

Yokawa, S., Suzuki, T., Hayashi, A., Inouye, S., Inoh, Y., Furuno, T.: Video-rate bioluminescence imaging of degranulation of mast cells attached to the extracellular matrix. Front. Cell Dev. Biol., 6, 74. (2018)


2017年

Inoh, Y., Haneda, A., Tadokoro, S., Yokawa, S., Furuno, T.: Cationic liposomes suppress intracellular calcium ion concentration increase via inhibition of PI3 kinase pathway in mast cells. Biochim. Biophys. Acta. 1859, 2461-2466. (2017)

Yokawa, S., Suzuki, T., Inouye, S., Inoh, Y., Suzuki, R., Kanamori, T., Furuno, T., Hirashima, N.: Visualization of glucagon secretion from pancreatic α cells by bioluminescence video microscopy: identification of secretion sites in the intercellular contact regions. Biochem. Biophys. Res. Commun., 485, 725-730. (2017)

Inoh, Y., Nagai, M., Matsushita, K., Nakanishi, M., Furuno. T.: Gene transfection efficiency into dendritic cells is influenced by the size of cationic liposomes/DNA complexes. Eur. J. Pharm. Sci., 102, 230-236. (2017)


2016年

Tadokoro, S., Shibata, T., Inoh, Y., Amano, T., Nakanishi, M., Hirashima, N., Utsunomiya-Tate, N.: Phosphorylation of syntaxin-3 at Thr 14 negatively regulates exocytosis in RBL-2H3 mast cells. Cell Biol. Int., 40, 589-596. (2016)

Yokawa, S., Furuno, T., Suzuki, T., Inoh, Y., Suzuki, R., Hirashima, N.: Effect of cell adhesion molecule 1 expression on intracellular granule movement in pancreatic α cells. Cell Biochem. Biophys., 74, 391-398. (2016)

Iino, T., Hagiyama, M., Furuno, T., Ito, A., Hosokawa, Y.: Time-courses statistical evaluation of intercellular adhesion maturation by single-cell adhesion measurement using femtosecond laser impulse. Biophys. J., 111, 2255-2262. (2016)


2015

Tadokoro, S., Inoh, Y., Nakanishi, M., Hirashima, N.: Effects of PIP2 on membrane fusion between mast cell SNARE liposomes mediated by synaptotagmin 2. Biochim. Biophys. Acta, 1848, 2290-2294. (2015)

Furuno, T., Shinkai, N., Inoh, Y., Nakanishi, M.: Impaired expression of the mitochondrial calcium uniporter suppresses mast cell degranulation. Mol. Cell. Biochem., 410, 215-221. (2015)



2014

Goto, S., Ozaki, Y., Suzumori, N., Yasukochi, A., Kawakubo, T., Furuno, T., Nakanishi, M., Yamamoto, K., Sugiura-Ogasawara, M.: Role of cathepsin E from decidual macrophages in patients with recurrent miscarriage. Mol. Hum. Reprod., 20, 454-462. (2014)

Obata, T., Suzuki, Y., Ogawa, N., Kurimoto, I., Yamamoto, H., Furuno, T., Sasaki, T., Tanaka, M.: Improvement of the antitumor activity of poorly soluble sapacitabine (CS-682) by using Soluplus® as a surfactant. Biol. Pharm. Bull., 37, 802-807. (2014)



2013

Hagiyama, M., Inoue, T., Furuno, T., Iino, T., Itami, S., Nakanishi, M., Asada, H., Hosokawa, Y., Ito, A.: Increased expression of cell adhesion molecule 1 by mast cells as a cause of enhanced nerve-mast cell interaction in a hapten-induced mouse model of atopic dermatitis. Br. J. Dermatol., 168, 771-778. (2013)

Inoh, Y., Furuno, T., Hirashima, N., Kitamoto, D., Nakanishi, M.: Synergistic effect of a biosurfactant and protamine on gene transfection efficiency. Eur. J. Pharm. Sci., 49, 1-9. (2013)

Nakanishi, M., Inoh, Y., Furuno, T.: New transfection agents based on liposomes containing biosurfactant MEL-A (review). Pharmaceutics, 5, 411-420. (2013)

Nakamura, M., Inoh, Y., Nakanishi, M., Furuno, T.: Substance P is an important role in cell adhesion molecule 1-mediated nerve-pancreatic islet α cell interaction. Biochem. Biophys. Res. Commun., 438, 563-567. (2013)

Inoh, Y., Tadokoro, S., Tanabe, H., Inoue, M., Hirashima, N., Nakanishi, M., Furuno, T.: Inhibitory effects of a cationic liposome on allergic reaction mediated by mast cell activation. Biochem. Pharmacol.,86, 1731-1738. (2013)

中西 守、古野忠秀:肥満細胞と感覚神経の接着におけるCADM1とネクチン-3の関与.生体の科学,64, 216-219. (2013)



2012

Furuno, T., Nakanishi, M.: Kefiran suppresses antigen-induced mast cell activation. Biol. Pharm. Bull., 35, 178-183. (2012)

Furuno, T., Hagiyama, M., Sekimura, M., Okamoto, K., Suzuki, R., Ito, A., Hirashima, N., Nakanishi, M.: Cell adhesion molecule 1 (CADM1) on mast cells promotes interaction with dorsal root ganglion neurites by heterophilic binding to nectin-3. J. Neuroimmunol., 250, 50-58. (2012)

Takekawa, M., Furuno, T., Hirashima, N., Nakanishi, M.: Mitochondria take up Ca2+ in two steps dependently on store-operated Ca2+ entry in mast cells. Biol. Pharm. Bull., 35, 1354-1360. (2012)



2011

Inoh, Y., Furuno, T., Hirashima, N., Kitamoto, D., Nakanishi, M.: Rapid delivery of small interfering RNA by biosurfactant MEL-A-containing liposomes. Biochem. Biophys. Res. Commun., 414, 635-640. (2011)

Furuno, T., Nakanishi, M.: Analysis of neuro-immune interactions by an in vitro co-culture approach, in Merighi, A. (Ed), Neuropeptides: Methods and Protocols, Methods in Molecular Biology vol. 789, Springer, pp171-180. (2011)

Hagiyama, M., Furuno, T., Hosokawa, Y., Iino, T., Ito, T., Inoue, T., Nakanishi, M., Murakami, Y., Ito, A.: Enhanced nerve-mast cell interaction by a neuronal short isoform of cell adhesion molecule-1, CADM1. J. Immunol., 186, 5983-5992. (2011)

Furuno, T., Nakanishi, M.: A rational approach to inducing neuronal differentiation in embryonic stem cells, in Lovrecic, K. (Ed), Embryonic Stem Cells: The Hormonal Regulation of Pluripotency and Embryogenesis, InTech, pp429-444. (2011)



2010

Inoh, Y., Furuno, T., Hirashima, N., Kitamoto, D., Nakanishi, M.: The ratio of unsaturated fatty acids in biosurfactants affects the efficiency of gene transfection. Int. J. Pharm., 398, 225-230. (2010)

Hiramatsu, H., Tadokoro, S., Nakanishi, M., Hirashima, N.: Latrotoxin-induced exocytosis in mast cells transfected with latrophilin. Toxicon, 56, 1372-1380. (2010)

Miyazu, S., Furuno, T, Nakanishi, M.: Phosphorylation states of STAT3 and ERKs in mouse embryonic stem cells. Cell Biol. Int., 34, 485-492. (2010)

Hoshino, Y., Hirashima, N., Nakanishi, M., Furuno, T.: Inhibition of degranulation and cytokine production in bone marrow-derived mast cells by hydrolyzed rice bran. Inflamm. Res., 59, 615-625. (2010)

Kawamura, F., Nakanishi, M., Hirashima, N.: Effects of menadione, a reactive oxygen generator, on leukotriene secretion from RBL-2H3 cells. Biol. Pharm. Bull., 33, 881-885. (2010)

Tadokoro, S., Nakanishi, M., Hirashima, N.: Complexin II regulates degranulation in RBL-2H3 cells by interacting with SNARE complex containing syntaxin-3. Cell. Immunol., 261, 51-56. (2010)



2009

Nakanishi, M., Inoh, Y., Kitamoto, D., Furuno, T.: Nano vectors with a biosurfactant for gene transfection and drug delivery (review). J. Drug Deliv. Sci. Tech., 19, 165-169. (2009)

Inoh, Y., Furuno, T., Hirashima, N., Nakanishi, M.: Non-viral vectors with a biosurfactant MEL-A promote gene transfection into solid tumors in mouse abdominal cavity. Biol. Pharm. Bull., 32, 126-128. (2009)

Sakiyama, H., Tadokoro, S., Nakanishi, M., Hirashima, N.: Membrane fusion between liposomes containing SNARE proteins involved in mast cell exocytosis. Inflamm. Res., 58, 139-142. (2009)

Sugimoto, Y., Furuno, T., Nakanishi, M.: Effect of NeuroD2 expression on neuronal differentiation in mouse embryonic stem cells. Cell Biol. Int., 33, 174-179. (2009)

中西 守、古野忠秀、柴田麻希:A passage to Algonquin ~自然との共生~. 愛知学院大学薬学会誌, 2, 11-14. (2009)

竹川まり恵、古野忠秀、中西 守:マスト細胞のミトコンドリア内カルシウムイオン動態とその役割. 愛知学院大学薬学会誌, 2, 27-30. (2009)



2008

Kumagai, K., Ozaki, Y., Nakanishi, T., Inomata, M., Furuno, T., Nakanishi, M., Ogasawara, M. S.: Role of μ-calpain in human decidua for recurrent miscarriage. Am. J. Reprod. Immunol., 59, 339-346. (2008)

Koma, Y., Furuno, T., Hagiyama, M., Hamaguchi, K., Nakanishi, M., Masuda, M., Hirota, S., Yokozaki, H., Ito, A.: Cell adhesion molecule 1 is a novel pancreatic-islet cell adhesion molecule that mediates nerve-islet cell interactions. Gastroenterology, 134, 1544-1554. (2008)

Nakanishi, M., Furuno, T.: Molecular basis of neuroimmune interaction in an in vitro coculture approach (review). Cell. Mol. Immunol., 5, 249-259. (2008)

Miura, K., Nomura, H., Nakanishi, M., Hirashima, N.: Munc13-1, an active zone protein, regulates exocytosis in mast cells. Bioimages, 16, 11-18. (2008)



2007

Chikamatsu, S., Furuno, T., Kinoshita, Y., Inoh, Y., Hirashima, N., Teshima, R., Nakanishi, M.: Effects of Cot expression on the nuclear translocation of NF-κB in RBL-2H3 cells. Mol. Immunol., 44, 1490-1497. (2007)

Ueno, Y., Hirashima, N., Inoh, Y., Furuno, T., Nakanishi, M.: Characterization of biosurfactant-containing liposomes and their efficiency for gene transfection. Biol. Pharm. Bull., 30, 169-172. (2007)

Tadokoro, S., Kurimoto, T., Nakanishi, M., Hirashima, N.: Munc18-2 regulates exocytotic membrane fusion positively interacting with syntaxin-3 in RBL-2H3 cells. Mol. Immunol., 44, 3427-3433. (2007)

Hirashima, N., Minatani, K., Hattori, Y., Ohwada, T., Nakanishi, M.: Anchoring cationic amphiphiles for nucleotide delivery: significance of DNA release from cationic liposomes for transfection. Biol Pharm Bull., 30, 1117-1122. (2007)

Ueno, Y., Inoh, Y., Furuno, T., Hirashima, N., Kitamoto, D., Nakanishi, M.: NBD-conjugated biosurfactant (MEL-A) shows a new pathway for transfection. J. Control. Release, 123, 247-253. (2007)

Suzuki, R., Furuno, T., Okamoto, K., Teshima, R., Nakanishi, M.: ATP plays a role in neurite stimulation with activated mast cells. J. Neuroimmunol., 192, 49-56. (2007)

Obata, K., Furuno, T., Nakanishi, M., Togari, A.: Direct neurite-osteoblastic cell communication, as demonstrated by use of an in vitro co-culture system. FEBS Lett., 581, 5917-5922. (2007)



2006

Furuno, T., Nakanishi, M.: Neurotrophic factors increase tumor necrosis factor-α-induced nuclear translocation of NF-κB in rat PC12 cells. Neurosci. Lett., 392, 240-244. (2006)

Kawamura, F., Hirashima, N., Furuno, T., Nakanishi, M.: The effects of 2-methyl-1,4-nephtoquinone (menadione) on cellular signaling in RBL-2H3 cells. Biol. Pharm. Bull., 29, 605-607. (2006)

Kato, N., Nakanishi, M., Hirashima, N.: Flotillin-1 regulates IgE receptor-mediated signaling in rat basophilic leukemia (RBL-2H3) cells. J. Immunol., 177, 147-154. (2006)

Nakamura, R., Furuno, T., Nakanishi, M.: The plasma membrane shuttling of CAPRI is related to regulation of mast cell activation. Biochem. Biophys. Res. Commun., 347, 363-368. (2006)

Amano, K., Furuno, T., Nakanishi, M.: Conditioned medium from feeder STO cells increases the attachment of mouse embryonic stem cells. Biol. Pharm. Bull., 29, 1747-1750. (2006)

Ishihara, Y., Furuno, T., Nakanishi, M.: The role of phosphatidylinositol 4-kinase type IIα on degranulation from RBL-2H3 cells. Inflamm. Res., 55, 465-468. (2006)

中西 守:機能のゆらぎ.薬学雑誌, 126, 379-393. (2006)



2005年

Furuno, T., Ito, A., Koma, Y., Watabe, K., Yokozaki, H., Bienenstock, J., Nakanishi, M., Kitamura, Y.: The spermatogenic Ig superfamily/synaptic cell adhesion molecule mast-cell adhesion molecule promotes interaction with nerves. J. Immunol., 174, 6934-6942. (2005)

Furuno, T., Nakanishi, M.: Live cell imaging to study signaling molecules in allergic reactions (review). Biol. Pharm. Bull., 28, 1551-1559. (2005)

Suzuki, A., Suzuki, R., Furuno, T., Teshima, R., Nakanishi, M.: Calcium response and FcεRI expression in bone marrow-derived mast cells co-cultured with SCG neurites. Biol. Pharm. Bull., 28, 1963-1965. (2005)

古野忠秀:顕微光学法によるマスト細胞活性化の分子機構の研究.薬学雑誌, 125, 671-683. (2005)


薬品分析学講座のホームページへ

愛知学院大学薬学部のホームページへ