伊納 義和 (いのう よしかず)


プロフィール

岐阜県土岐市出身
名古屋市立大学薬学部卒業、名古屋市立大学大学院薬学研究科博士後期課程修了後、
アピ株式会社長良川リサーチセンターを経て、
愛知学院大学薬学部助手(2006年1月より)
愛知学院大学薬学部助教(2007年4月より)
愛知学院大学薬学部講師(2010年9月より)
愛知学院大学薬学部准教授(2020年4月より)



研究業績

(英語原論文)

1) Inoh, Y., Kitamoto, D., Hirashima, N., Nakanishi, M.: Biosurfactants of MEL-A increase gene transfection mediated by cationic liposomes. Biochem. Biophys. Res. Commun., 289, 57-61. (2001)

2) Inoh, Y., Kitamoto, D., Hirashima, N., Nakanishi, M.: Biosurfactant MEL-A dramatically increases gene transfection via membrane fusion. J. Control. Release, 94, 423-431. (2004)

3) Mishima, S., Narita, Y., Chikamatsu, S., Inoh, Y., Ohta, S., Yoshida, C., Araki, Y., Akao, Y., Suzuki, K. M., Nozawa, Y.: Effects of propolis on cell growth and gene expression in HL-60 cells. J. Ethnopharmacol., 99, 5-11. (2005)

4) Mishima, S., Inoh, Y., Narita, Y., Ohta, S., Sakamoto, T., Araki, Y., Suzuki, K. M., Akao, Y., Nozawa, Y.: Identification of caffeoylquinic acid derivatives from Brazilian propolis as constituents invloved in induction of granulocytic differentiation in HL-60 cells. Bioorg. Med. Chem., 13, 5814-5818. (2005)

5) Narita, Y., Nomura, J., Ohta, S., Inoh, Y., Suzuki, K. M., Araki, Y., Okada, S., Matsumoto, I., Isohama, Y., Abe, K., Miyata, T., Mishima, S.: Royal jelly stimulates bone formation: physiologic and nutrigenomic studies with mice and cell lines. Biosci. Biotechnol. Biochem., 70, 2508-2514. (2006)

6) Chikamatsu, S., Furuno, T., Kinoshita, Y., Inoh, Y., Hirashima, N., Teshima, R., Nakanishi, M.: Effects of Cot expression on the nuclear translocation of NF-κB in RBL-2H3 cells. Mol. Immunol., 44, 1490-1497. (2007)

7) Ueno, Y., Hirashima, N., Inoh, Y., Furuno, T., Nakanishi, M.: Characterization of biosurfactant-containing liposomes and their efficiency for gene transfection. Biol. Pharm. Bull., 30, 169-172. (2007)

8) Ueno, Y., Inoh, Y., Furuno, T., Hirashima, N., Kitamoto, D., Nakanishi, M.: NBD-conjugated biosurfactant (MEL-A) shows a new pathway for transfection. J. Control. Release, 123, 247-253. (2007)

9) Inoh, Y., Furuno, T., Hirashima, N., Nakanishi, M.: Non-viral vectors with a biosurfactant MEL-A promote gene transfection into solid tumors in mouse abdominal cavity. Biol. Pharm. Bull., 32, 126-128. (2009)

10) Nakanishi, M., Inoh, Y., Kitamoto, D., Furuno, T.: Nano vectors with a biosurfactant for gene transfection and drug delivery (review). J. Drug Deliv. Sci. Tech., 19, 165-169. (2009)

11) Inoh, Y., Furuno, T., Hirashima, N., Kitamoto, D., Nakanishi, M.: The ratio of unsaturated fatty acids in biosurfactants affects the efficiency of gene transfection. Int. J. Pharm., 398, 225-230. (2010).

12) Inoh, Y., Furuno, T., Hirashima, N., Kitamoto, D., Nakanishi, M.: Rapid delivery of small interfering RNA by biosurfactant MEL-A-containing liposomes. Biochem. Biophys. Res. Commun., 414, 635-640. (2011).

13) Inoh, Y., Furuno, T., Hirashima, N., Kitamoto, D., Nakanishi, M.: Synergistic effect of a biosurfactant and protamine on gene transfection efficiency. Eur. J. Pharm. Sci., 49, 1-9. (2013)

14) Nakanishi, M., Inoh, Y., Furuno, T.: New transfection agents based on liposomes containing biosurfactant MEL-A (review). Pharmaceutics, 5, 411-420. (2013)

15) Nakamura, M., Inoh, Y., Nakanishi, M., Furuno, T.: Substance P is an important role in cell adhesion molecule 1-mediated nerve-pancreatic islet α cell interaction. Biochem. Biophys. Res. Commun., 438, 563-567. (2013)

16) Inoh, Y., Tadokoro, S., Tanabe, H., Inoue, M., Hirashima, N., Nakanishi, M., Furuno, T.: Inhibitory effects of a cationic liposome on allergic reaction mediated by mast cell activation. Biochem. Pharmacol., 86, 1731-1738. (2013)

17) Tadokoro, S., Inoh, Y., Nakanishi, M., Hirashima, N.: Effects of PIP2 on membrane fusion between mast cell SNARE liposomes mediated by synaptotagmin 2. Biochim. Biophys. Acta, 1848, 2290-2294. (2015)

18) Furuno, T., Shinkai, N., Inoh, Y., Nakanishi, M.: Impaired expression of the mitochondrial calcium uniporter suppresses mast cell degranulation. Mol. Cell. Biochem., 410, 215-221. (2015)

19) Tadokoro, S., Shibata, T., Inoh, Y., Amano, T., Nakanishi, M., Hirashima, N., Utsunomiya-Tate, N.: Phosphorylation of syntaxin-3 at Thr 14 negatively regulates exocytosis in RBL-2H3 mast cells. Cell Biol. Int., 40, 589-596. (2016)

20) Yokawa, S., Furuno, T., Suzuki, T., Inoh, Y., Suzuki, R., Hirashima, N.: Effect of cell adhesion molecule 1 expression on intracellular granule movement in pancreatic α cells. Cell Biochem. Biophys., 74, 391-398. (2016)

21) Yokawa, S., Suzuki, T., Inouye, S., Inoh, Y., Suzuki, R., Kanamori, T., Furuno, T., Hirashima, N.: Visualization of glucagon secretion from pancreatic α cells by bioluminescence video microscopy: identification of secretion sites in the intercellular contact regions. Biochem. Biophys. Res. Commun., 485, 725-730. (2017)

22) Inoh, Y., Nagai, M., Matsushita, K., Nakanishi, M., Furuno. T.: Gene transfection efficiency into dendritic cells is influenced by the size of cationic liposomes/DNA complexes. Eur. J. Pharm. Sci., 102, 230-236. (2017)

23) Inoh, Y., Haneda, A., Tadokoro, S., Yokawa, S., Furuno, T.: Cationic liposomes suppress intracellular calcium ion concentration increase via inhibition of PI3 kinase pathway in mast cells. Biochim. Biophys. Acta. 1859, 2461-2466. (2017)

24) Watabe, K., Yokawa, S., Inoh, Y., Suzuki, T., Furuno, T.: Decreased intracellular granule movement and glucagon secretion in pancreatic α cells attached to superior cervical ganglion neurites. Mol. Cell. Biochem., 446, 83-89. (2018)

25) Yokawa, S., Suzuki, T., Hayashi, A., Inouye, S., Inoh, Y., Furuno, T.: Video-rate bioluminescence imaging of degranulation of mast cells attached to the extracellular matrix. Front. Cell Dev. Biol., 6, 74. (2018)

26) Shiki, A., Inoh, Y., Yokawa, S., Furuno, T.: Promotion of microtubule acetylation plays an important role in degranulation of antigen-activated mast cells. Inflamm. Res., 68, 181-184. (2019)

27) Shiki, A., Inoh, Y., Yokawa, S., Furuno, T.: Inhibition of degranulation in mast cells attached to a hydrogel through defective microtubule tracts. Exp. Cell Res., 381, 248-255. (2019)

28) Suzuki, R., Inoh, Y., Yokawa, S., Suzuki, R., Furuno, T., Hirashima, N.: Monomer hapten and hapten-specific IgG inhibit mast cell activation evoked by multivalent hapten with different mechanisms. Eur. J. Immunol., 49, 2172-2183. (2019)

29) Inoh, Y., Tsuchiya, Y., Nakanishi, Y., Yokawa, S., Furuno, T.: Involvement of intracellular caveolin-1 distribution in the suppression of antigen-induced mast cell activation by cationic liposomes. Cell Biol. Int., 44, 1068-1075. (2020)

30) Inoh, Y., Hirose, T., Yokoi, A., Yokawa, S., Furuno, T.: Effects of lipid composition in cationic liposomes on suppression of mast cell activation. Chem. Phys. Lipids, 231, 104948. (2020)

31) Suuki, R., Inoh ,Y., Yokawa, S., Furuno, T., Hirashima, N.: Receptor dynamics regulates actin polymerization state through phosphorylation of cofilin in mast cells. Biochem. Biophys. Res. Commun., 534, 714-719. (2021)


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